Experts and Doctors on high mobility group proteins in Clayton, Victoria, Australia
Locale: Clayton, Victoria, Australia
Topic: high mobility group proteins
Kasimiotis H, Myers M, Argentaro A, Mertin S, Fida S, Ferraro T, et al
. Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets. Diabetes. 2000;49:555-61 pubmed
Fida S, Myers M, Mackay I, Zimmet P, Mohan V, Deepa R, et al
. Antibodies to diabetes-associated autoantigens in Indian patients with Type 1 diabetes: prevalence of anti-ICA512/IA2 and anti-SOX13. Diabetes Res Clin Pract. 2001;52:205-11 pubmed
Britt K, Kerr J, O Donnell L, Jones M, Drummond A, Davis S, et al
. Estrogen regulates development of the somatic cell phenotype in the eutherian ovary. FASEB J. 2002;16:1389-97 pubmed
..These findings constitute definitive evidence that estrogen plays a critical role in maintaining female somatic interstitial and granulosa cells in the eutherian ovary. ..
Fida S, Myers M, Whittingham S, Rowley M, Ozaki S, Mackay I. Autoantibodies to the transcriptional factor SOX13 in primary biliary cirrhosis compared with other diseases. J Autoimmun. 2002;19:251-7 pubmed
..Anti-SOX13 in PBC may occur merely as an immune response to products of damage to parenchymal tissue, or may be illustrative of a general proclivity of transcriptional regulatory proteins to elicit autoimmune responses. ..
Harley V, Clarkson M, Argentaro A. The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group (HMG) box 9]. Endocr Rev. 2003;24:466-87 pubmed
..Many genes, however, remain unidentified, because in the majority of cases of XY females and in all cases of XX males lacking SRY, the mutated gene is unknown. ..
Davies R, Wagstaff K, McLaughlin E, Loveland K, Jans D. The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins. Biochim Biophys Acta. 2013;1833:3436-3444 pubmed publisher
..These results imply for the first time that BRAP2 may have an important role in modulating subcellular localization during testicular development. ..