Experts and Doctors on bone marrow cells in South Brisbane, Queensland, Australia


Locale: South Brisbane, Queensland, Australia
Topic: bone marrow cells

Top Publications

  1. Williams S, Wreschner D, Tran M, Eyre H, Sutherland G, McGuckin M. Muc13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells. J Biol Chem. 2001;276:18327-36 pubmed
    ..MUC13 is cleaved, and the beta-subunit containing the cytoplasmic tail undergoes homodimerization. Including MUC13, there are at least five cell surface mucins expressed in the gastrointestinal tract. ..
  2. Levesque J, Winkler I, Hendy J, Williams B, Helwani F, Barbier V, et al. Hematopoietic progenitor cell mobilization results in hypoxia with increased hypoxia-inducible transcription factor-1 alpha and vascular endothelial growth factor A in bone marrow. Stem Cells. 2007;25:1954-65 pubmed
    ..Disclosure of potential conflicts of interest is found at the end of this article. ..
  3. Ju X, Clark G, Hart D. Review of human DC subtypes. Methods Mol Biol. 2010;595:3-20 pubmed publisher
    ..We also hope to clarify the differences in nomenclature between the human and mouse models that have arisen by way of the different experimental models. ..
  4. Winkler I, Sims N, Pettit A, Barbier V, Nowlan B, Helwani F, et al. Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs. Blood. 2010;116:4815-28 pubmed publisher
    ..Together, these results establish that bone marrow macrophages are pivotal to maintain the endosteal HSC niche and that the loss of such macrophages leads to the egress of HSCs into the blood. ..
  5. Winkler I, Barbier V, Nowlan B, Jacobsen R, Forristal C, Patton J, et al. Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance. Nat Med. 2012;18:1651-7 pubmed publisher
    ..As bone marrow suppression is a severe side effect of high-dose chemotherapy, transient blockade of E-selectin is potentially a promising treatment for the protection of HSCs during chemotherapy or irradiation. ..