Experts and Doctors on amino acids in Sydney, New South Wales, Australia


Locale: Sydney, New South Wales, Australia
Topic: amino acids

Top Publications

  1. Bell K, Petocz P, Colagiuri S, Brand Miller J. Algorithms to Improve the Prediction of Postprandial Insulinaemia in Response to Common Foods. Nutrients. 2016;8:210 pubmed publisher
    ..Knowledge of the GI or glycaemic response to 1000 kJ portions together with nutrient composition therefore provides a good approximation for ranking of foods according to their "insulin demand". ..
  2. Nivison Smith L, Collin S, Zhu Y, Ready S, Acosta M, Hunt D, et al. Retinal amino acid neurochemistry of the southern hemisphere lamprey, Geotria australis. PLoS ONE. 2013;8:e58406 pubmed publisher
    ..On the other hand, metabolic elements of the retina such as neurotransmitter precursor amino acids and Müller cells are more sensitive to environmental changes associated with migration. ..
  3. Golombick T, Diamond T, Manoharan A, Ramakrishna R. Monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and curcumin: a randomized, double-blind placebo-controlled cross-over 4g study and an open-label 8g extension study. Am J Hematol. 2012;87:455-60 pubmed publisher
    ..Serum creatinine levels tended to diminish on curcumin therapy. These findings suggest that curcumin might have the potential to slow the disease process in patients with MGUS and SMM. ..
  4. Engel M, Snikeris P, Matosin N, Newell K, Huang X, Frank E. mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia. Psychopharmacology (Berl). 2016;233:1349-59 pubmed publisher
    ..This study significantly contributes to our understanding of the mechanisms underlying the therapeutic effects of LY379268 and supports the use of agents aimed at mGluR2/3. ..
  5. Pattison D, Davies M. Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress. Biochemistry. 2004;43:4799-809 pubmed
    ..Overall, these results shed light on the mechanisms of cell damage induced by HOX and indicate, for example, that the 3-chloro-Tyr:3-bromo-Tyr ratio does not reflect the relative roles of HOCl and HOBr in disease processes. ..
  6. Garner J, Harding M. Design and synthesis of alpha-helical peptides and mimetics. Org Biomol Chem. 2007;5:3577-85 pubmed
    ..Examples where synthetic compounds have delivered promising biological results will be highlighted as well as opportunities for the design of mimetics of the type I alpha-helical antifreeze proteins. ..
  7. Rodgers K. Non-protein amino acids and neurodegeneration: the enemy within. Exp Neurol. 2014;253:192-6 pubmed publisher
    ..We make the case that insidious entry of non-protein amino acids into the human food chain and their incorporation into protein might be contributing significantly to neurodegenerative damage. ..
  8. Kalloniatis M, Loh C, Acosta M, Tomisich G, Zhu Y, Nivison Smith L, et al. Retinal amino acid neurochemistry in health and disease. Clin Exp Optom. 2013;96:310-32 pubmed publisher
    ..An internet-based database of retinal images of amino acid labelling patterns and other amino acid-related images in health and disease is located at ..
  9. Church W, Jones K, Kuiper D, Shine J, Iismaa T. Molecular modelling and site-directed mutagenesis of human GALR1 galanin receptor defines determinants of receptor subtype specificity. Protein Eng. 2002;15:313-23 pubmed
    ..Our model supports previous reports of Phe282 of hGALR1 interacting with Trp2 of galanin and His264 of hGALR1 interacting with Tyr9 of galanin. ..

More Information


  1. Dance I. The mechanistically significant coordination chemistry of dinitrogen at FeMo-co, the catalytic site of nitrogenase. J Am Chem Soc. 2007;129:1076-88 pubmed
  2. Ting L, Williams T, Cowley M, Lauro F, Guilhaus M, Raftery M, et al. Cold adaptation in the marine bacterium, Sphingopyxis alaskensis, assessed using quantitative proteomics. Environ Microbiol. 2010;12:2658-76 pubmed publisher
    ..This study is also a benchmark for comparative proteomic analyses with other important marine bacteria and other cold-adapted organisms. ..
  3. Foo L, Zhang Q, Zhu K, Ma G, Hu X, Greenfield H, et al. Low vitamin D status has an adverse influence on bone mass, bone turnover, and muscle strength in Chinese adolescent girls. J Nutr. 2009;139:1002-7 pubmed publisher
    ..These findings suggest that adequate vitamin D status during adolescence is important for optimizing bone mass, which may lead to higher peak bone mass at maturity. Poor vitamin D status also compromises forearm muscle strength. ..
  4. Vullo D, Del Prete S, Osman S, Alasmary F, Alothman Z, Donald W, et al. Comparison of the amine/amino acid activation profiles of the ?- and ?-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei. J Enzyme Inhib Med Chem. 2018;33:25-30 pubmed publisher
  5. Fanson B, Taylor P. Additive and interactive effects of nutrient classes on longevity, reproduction, and diet consumption in the Queensland fruit fly (Bactrocera tryoni). J Insect Physiol. 2012;58:327-34 pubmed publisher
    ..These results indicate a need for caution when interpreting effects of dietary yeast as effects of protein. ..
  6. Suryo Rahmanto A, Davies M. Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides. Free Radic Biol Med. 2011;51:2288-99 pubmed publisher
    ..Overall, these findings demonstrate that SeMet may play an important role in the catalytic removal of damaging peptide and protein oxidation products. ..
  7. Fanson B, Taylor P. Protein:carbohydrate ratios explain life span patterns found in Queensland fruit fly on diets varying in yeast:sugar ratios. Age (Dordr). 2012;34:1361-8 pubmed publisher
    ..Finally, Q-flies adjusted their diet intake in response to P:C ratios and diet concentration. Our results substantiate recent claims that P:C ratios significantly modulate life span in flies. ..
  8. Ho Y, Abecasis A, Theys K, Deforche K, Dwyer D, Charleston M, et al. HIV-1 gp120 N-linked glycosylation differs between plasma and leukocyte compartments. Virol J. 2008;5:14 pubmed publisher
    ..These findings could also have relevance in shielding and evasion of HIV-1 from neutralizing antibodies. ..
  9. Lee H, Mun H, Lewis N, Crouch M, Culverston E, Mason R, et al. Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation. Biochem J. 2007;404:141-9 pubmed
  10. Stack C, Lowther J, Cunningham E, Donnelly S, Gardiner D, Trenholme K, et al. Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase. A protease involved in amino acid regulation with potential for antimalarial drug development. J Biol Chem. 2007;282:2069-80 pubmed
    ..Availability of functionally active recombinant PfLAP, coupled with a simple enzymatic readout, will aid medicinal chemistry and/or high throughput approaches for the future design/discovery of new antimalarial drugs. ..
  11. Biagini G, Yarlett N, Ball G, Billetz A, Lindmark D, Martinez M, et al. Bacterial-like energy metabolism in the amitochondriate protozoon Hexamita inflata. Mol Biochem Parasitol. 2003;128:11-9 pubmed
    ..This study also indicates that, as with other amitochondriate protozoa and some bacteria, the ADH pathway significantly contributes to the energy yield of the cell, particularly under O(2)-limited conditions...
  12. Carpenter K, Wiley V. Application of tandem mass spectrometry to biochemical genetics and newborn screening. Clin Chim Acta. 2002;322:1-10 pubmed
    ..This review covers some of the basic theory of MS/MS and focuses on the practical application of the technique in these two interrelated areas. ..
  13. Warren C. Post-uptake metabolism affects quantification of amino acid uptake. New Phytol. 2012;193:522-31 pubmed publisher
    ..Alternatively, post-uptake metabolism and transport could be minimized by harvesting plants within minutes of isotope addition...
  14. Jaratlerdsiri W, Rodríguez Zárate C, Isberg S, Damayanti C, Miles L, Chansue N, et al. Distribution of endogenous retroviruses in crocodilians. J Virol. 2009;83:10305-8 pubmed publisher
    ..Interestingly, CERV 1 was found only in crocodiles (Crocodylidae). The data generated here could assist future studies aimed at identifying orthologous and paralogous ERVs among crocodilians...
  15. Rodgers K, Shiozawa N. Misincorporation of amino acid analogues into proteins by biosynthesis. Int J Biochem Cell Biol. 2008;40:1452-66 pubmed publisher
    ..We confine the review to studies in which the synthetic machinery of cell has not been modified to accept non-protein amino acids. ..
  16. Yan W, Armishaw C, Goyette J, Yang Z, Cai H, Alewood P, et al. Mast cell and monocyte recruitment by S100A12 and its hinge domain. J Biol Chem. 2008;283:13035-43 pubmed publisher
    ..Interaction is unlikely to occur via the receptor for advanced glycation end products but, rather, via a G-protein-coupled mechanism. ..
  17. Huang M, Sivagurunathan S, Ting S, Jansson P, Austin C, Kelly M, et al. Molecular and functional alterations in a mouse cardiac model of Friedreich ataxia: activation of the integrated stress response, eIF2? phosphorylation, and the induction of downstream targets. Am J Pathol. 2013;183:745-57 pubmed publisher
    ..Thus, the pathogenesis of cardiomyopathy in FA correlates with the early and persistent eIF2? phosphorylation, which precedes activation of autophagy and apoptosis. ..
  18. Maroulis S, Schofield P, Edwards M. Osmoregulation in the parasitic protozoan Tritrichomonas foetus. Appl Environ Microbiol. 2003;69:4527-33 pubmed
    ..However, inhibitors of Na(+)-K(+)-2Cl(-) cotransport in other systems, such as quinine, ouabain, furosemide, and bumetanide, had no effect on the RVI or K(+) influx in T. foetus...
  19. Piper M, Soultoukis G, Blanc E, Mesaros A, Herbert S, Juricic P, et al. Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. Cell Metab. 2017;25:610-621 pubmed publisher
    ..Exome matching also enhanced mouse growth, indicating that it can be applied to other organisms whose genome sequence is known. ..