Experts and Doctors on conserved sequence in Queensland, Australia
Locale: Queensland, Australia
Topic: conserved sequence
Byrne K, Vuocolo T, Gondro C, White J, Cockett N, Hadfield T, et al
. A gene network switch enhances the oxidative capacity of ovine skeletal muscle during late fetal development. BMC Genomics. 2010;11:378 pubmed publisher
..These changes probably underpin the adaption of muscle to new physiological demands in the postnatal environment. ..
Subramanian S. Fixation of deleterious mutations at critical positions in human proteins. Mol Biol Evol. 2011;28:2687-93 pubmed publisher
Case R, Sharp E, Benned Jensen T, Rosenkilde M, Davis Poynter N, Farrell H. Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: ablation of constitutive signaling is associated with an attenuated phenotype in vivo. J Virol. 2008;82:1884-98 pubmed
..In addition, HCMV UL33 was found to partially compensate for the lack of M33 in vivo, suggesting conserved biological roles of the UL33 gene family...
Norwood S, Shaw D, Cowieson N, Owen D, Teasdale R, Collins B. Assembly and solution structure of the core retromer protein complex. Traffic. 2011;12:56-71 pubmed publisher
..Solution studies of the retromer core using small-angle X-ray scattering allow us to propose a model whereby VPS35 forms an extended platform with VPS29 and VPS26 bound at distal ends, with the potential for forming dimeric assemblies. ..
Shao R, Barker S. Chimeric mitochondrial minichromosomes of the human body louse, Pediculus humanus: evidence for homologous and non-homologous recombination. Gene. 2011;473:36-43 pubmed publisher
..Our analyses of the nucleotide sequences of chimeric mt minichromosomes indicate both homologous and non-homologous recombination between minichromosomes in the mitochondria of the human body louse...
Goire N, Freeman K, Tapsall J, Lambert S, Nissen M, Sloots T, et al
. Enhancing gonococcal antimicrobial resistance surveillance: a real-time PCR assay for detection of penicillinase-producing Neisseria gonorrhoeae by use of noncultured clinical samples. J Clin Microbiol. 2011;49:513-8 pubmed publisher
..gonorrhoeae penicillin resistance and is of particular relevance to regions where penicillin is still used to treat gonorrhea. ..
Nafisinia M, Riley L, Gold W, Bhattacharya K, Broderick C, Thorburn D, et al
. Compound heterozygous mutations in glycyl-tRNA synthetase (GARS) cause mitochondrial respiratory chain dysfunction. PLoS ONE. 2017;12:e0178125 pubmed publisher
..Together these studies provide evidence that the identified compound heterozygous GARS variants may be the cause of the mitochondrial dysfunction in our patient. ..
Moore S, Hale P, Byrne K. NCAM: a polymorphic microsatellite locus conserved across eutherian mammal species. Anim Genet. 1998;29:33-6 pubmed
..Polymorphisms were seen across five mammalian orders, in rat, buffalo, sheep, cow, whale and dolphin, with polymorphisms predicted in pig and dugong based on the length of the uninterrupted dinucleotide repeat...
Ripoll V, Irvine K, Ravasi T, Sweet M, Hume D. Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. J Immunol. 2007;178:6557-66 pubmed
..Thus, GPNMB acts as a negative regulator of macrophage inflammatory responses. ..