Experts and Doctors on amino acid motifs in Queensland, Australia
Locale: Queensland, Australia
Topic: amino acid motifs
Wijffels G, Johnson W, Oakley A, Turner K, Epa V, Briscoe S, et al
. Binding inhibitors of the bacterial sliding clamp by design. J Med Chem. 2011;54:4831-8 pubmed publisher
..We report the crystal structure of the complex containing one of these inhibitors, a biphenyl oxime, bound to ?(2), as a starting point for further inhibitor design. ..
Wijffels G, Dalrymple B, Prosselkov P, Kongsuwan K, Epa V, Lilley P, et al
. Inhibition of protein interactions with the beta 2 sliding clamp of Escherichia coli DNA polymerase III by peptides from beta 2-binding proteins. Biochemistry. 2004;43:5661-71 pubmed
..The hierarchy of peptide binding may be indicative of a competitive hierarchy for the binding of proteins to beta(2) in various stages or circumstances of DNA replication and repair. ..
Day B, To C, Himanen J, Smith F, Nikolov D, Boyd A, et al
. Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3. J Biol Chem. 2005;280:26526-32 pubmed
Papp L, Lu J, Striebel F, Kennedy D, Holmgren A, Khanna K. The redox state of SECIS binding protein 2 controls its localization and selenocysteine incorporation function. Mol Cell Biol. 2006;26:4895-910 pubmed
Pagan J, Arnold J, Hanchard K, Kumar R, Bruno T, Jones M, et al
. A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. J Biol Chem. 2007;282:15248-57 pubmed
Case R, Sharp E, Benned Jensen T, Rosenkilde M, Davis Poynter N, Farrell H. Functional analysis of the murine cytomegalovirus chemokine receptor homologue M33: ablation of constitutive signaling is associated with an attenuated phenotype in vivo. J Virol. 2008;82:1884-98 pubmed
..In addition, HCMV UL33 was found to partially compensate for the lack of M33 in vivo, suggesting conserved biological roles of the UL33 gene family...
Brooks A, Dai W, O Mara M, Abankwa D, Chhabra Y, Pelekanos R, et al
. Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science. 2014;344:1249783 pubmed publisher
..This model may well generalize to other class I cytokine receptors. ..
He Y, Hryciw D, Carroll M, Myers S, Whitbread A, Kumar S, et al
. The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. J Biol Chem. 2008;283:24000-10 pubmed publisher
..These data, indicating that Nedd4-2 differentially interacts with and regulates TTYH1-3, will be important for understanding mechanisms controlling Tweety proteins in physiology and disease. ..
Norwood S, Shaw D, Cowieson N, Owen D, Teasdale R, Collins B. Assembly and solution structure of the core retromer protein complex. Traffic. 2011;12:56-71 pubmed publisher
..Solution studies of the retromer core using small-angle X-ray scattering allow us to propose a model whereby VPS35 forms an extended platform with VPS29 and VPS26 bound at distal ends, with the potential for forming dimeric assemblies. ..