Experts and Doctors on proline in Canberra, Australian Capital Territory, Australia


Locale: Canberra, Australian Capital Territory, Australia
Topic: proline

Top Publications

  1. Webb D, Rosenberg H, Cox G. Mutational analysis of the Escherichia coli phosphate-specific transport system, a member of the traffic ATPase (or ABC) family of membrane transporters. A role for proline residues in transmembrane helices. J Biol Chem. 1992;267:24661-8 pubmed
    ..The double mutation in the PstA protein resulted in a permanently "closed" system, whereas the double mutation in the PstC protein resulted in a permanently "open" transport system...
  2. Sloper Mould K, Eyre H, Wang X, Sutherland G, Baker R. Characterization and chromosomal localization of USP3, a novel human ubiquitin-specific protease. J Biol Chem. 1999;274:26878-84 pubmed
    ..USP3 is also only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond. ..
  3. Blackburn A, Coggan M, Tzeng H, Lantum H, Polekhina G, Parker M, et al. GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase. Pharmacogenetics. 2001;11:671-8 pubmed
    ..The different amino acid substitutions have been mapped on to the recently determined crystal structure of GSTZ1-1 to evaluate and explain their influence on function. ..
  4. Ayliffe M, Roberts J, Mitchell H, Zhang R, Lawrence G, Ellis J, et al. A plant gene up-regulated at rust infection sites. Plant Physiol. 2002;129:169-80 pubmed publisher
    ..The promoters of these genes have potential roles for the engineering of synthetic rust resistance genes by targeting transgene expression to the sites of rust infection...
  5. Angelats C, Wang X, Jermiin L, Copeland N, Jenkins N, Baker R. Isolation and characterization of the mouse ubiquitin-specific protease Usp15. Mamm Genome. 2003;14:31-46 pubmed
    ..Phylogenetic studies suggest that a sequence currently identified as a chicken Usp4 ortholog is in fact a USP15 ortholog, while bona-fide chicken, cow, and rat Usp4 orthologs can be identified in EST databases. ..
  6. Jones A, Hulett M, Parish C. Histidine-rich glycoprotein binds to cell-surface heparan sulfate via its N-terminal domain following Zn2+ chelation. J Biol Chem. 2004;279:30114-22 pubmed
    ..Based on these data, we propose that the N1N2 domain binds to cell-surface heparan sulfate and that the interaction of Zn2+ with the HRR can indirectly enhance cell-surface binding. ..
  7. Kowalczuk S, Bröer A, Munzinger M, Tietze N, Klingel K, Broer S. Molecular cloning of the mouse IMINO system: an Na+- and Cl--dependent proline transporter. Biochem J. 2005;386:417-22 pubmed
    ..Accordingly we suggest that the two homologues be termed 'XT3s1 IMINO(B)' and 'XT3 IMINO(K)' to indicate the tissue expression of the two genes. ..
  8. Mitchell H, Ayliffe M, Rashid K, Pryor A. A rust-inducible gene from flax (fis1) is involved in proline catabolism. Planta. 2006;223:213-22 pubmed
    ..These data indicate that the fis1 gene plays a role in proline metabolism and most likely encodes for a P5CDH enzyme. However, the precise role of fis1 and P5C catabolism in the development of rust disease remains unclear. ..
  9. Bröer A, Tietze N, Kowalczuk S, Chubb S, Munzinger M, Bak L, et al. The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2). Biochem J. 2006;393:421-30 pubmed
    ..A mouse B(0)AT2-like transport activity was detected in synaptosomes and cultured neurons. A potential role of B(0)AT2 in transporting neurotransmitter precursors and neuromodulators is proposed. ..

More Information


  1. Bröer A, Balkrishna S, Kottra G, Davis S, Oakley A, Broer S. Sodium translocation by the iminoglycinuria associated imino transporter (SLC6A20). Mol Membr Biol. 2009;26:333-46 pubmed publisher
    ..The proposed homology model allows to study mutations in IMINO associated with iminoglycinuria. ..