Experts and Doctors on insertional mutagenesis in Canberra, Australian Capital Territory, Australia


Locale: Canberra, Australian Capital Territory, Australia
Topic: insertional mutagenesis

Top Publications

  1. Margis Pinheiro M, Zhou X, Zhu Q, Dennis E, Upadhyaya N. Isolation and characterization of a Ds-tagged rice (Oryza sativa L.) GA-responsive dwarf mutant defective in an early step of the gibberellin biosynthesis pathway. Plant Cell Rep. 2005;23:819-33 pubmed publisher
    ..All OsKS1-like genes are transcribed with different expression patterns. ESTs corresponding to all six OsKS genes are represented in other cereal databases including barley, wheat and maize, suggesting that they are biologically active...
  2. Sheldon C, Finnegan E, Dennis E, Peacock W. Quantitative effects of vernalization on FLC and SOC1 expression. Plant J. 2006;45:871-83 pubmed
    ..In addition, we show that SOC1 undergoes an acute induction by both short and long cold exposures. ..
  3. Delaney S, Hayward D, Barleben F, Fischbach K, Miklos G. Molecular cloning and analysis of small optic lobes, a structural brain gene of Drosophila melanogaster. Proc Natl Acad Sci U S A. 1991;88:7214-8 pubmed
    ..By constructing transgenic flies carrying a single wild-type copy of the sol gene in a homozygous sol mutant background, we have restored the normal neuroanatomical phenotype to individuals that would have developed mutant brains. ..
  4. Wilson K, Sessitsch A, Corbo J, Giller K, Akkermans A, Jefferson R. beta-Glucuronidase (GUS) transposons for ecological and genetic studies of rhizobia and other gram-negative bacteria. Microbiology. 1995;141 ( Pt 7):1691-705 pubmed
    ..The variety of assays available for GUS enable both quantitative assays and spatial localization of marked bacteria to be carried out. ..
  5. ten Have J, Green M, Howells A. Molecular characterization of spontaneous mutations at the scarlet locus of Drosophila melanogaster. Mol Gen Genet. 1995;249:673-81 pubmed
    ..The results show that the same types of transposable elements that cause spontaneous mutation in laboratory stocks of D. melanogaster also cause mutation in the wild...
  6. Neylon C, Brown S, Kralicek A, Miles C, Love C, Dixon N. Interaction of the Escherichia coli replication terminator protein (Tus) with DNA: a model derived from DNA-binding studies of mutant proteins by surface plasmon resonance. Biochemistry. 2000;39:11989-99 pubmed
    ..The kinetic and thermodynamic data suggest a model for Tus binding to TerB which involves an ordered series of events that include structural changes in the protein. ..
  7. Millar A, Jacobsen J, Ross J, Helliwell C, Poole A, Scofield G, et al. Seed dormancy and ABA metabolism in Arabidopsis and barley: the role of ABA 8'-hydroxylase. Plant J. 2006;45:942-54 pubmed
    ..Our results point to a pivotal role for the ABA 8'-hydroxylase gene in controlling dormancy and that the action of this enzyme may be confined to a particular organ as in the coleorhiza of cereals. ..
  8. Adams M, van Leeuwen B, McFadden G, Kerr P. Construction and testing of a novel host-range defective myxoma virus vaccine with the M063 gene inactivated that is non-permissive for replication in rabbit cells. Vet Res. 2008;39:60 pubmed publisher
    ..Seasonal boosting would be predicted to provide long-term protection. Targeted host-range gene deletions could have potential for rapid development of poxvirus vaccines in general...
  9. Wilson P, Estavillo G, Field K, Pornsiriwong W, Carroll A, Howell K, et al. The nucleotidase/phosphatase SAL1 is a negative regulator of drought tolerance in Arabidopsis. Plant J. 2009;58:299-317 pubmed publisher

More Information


  1. Zhu Q, Upadhyaya N, Gubler F, Helliwell C. Over-expression of miR172 causes loss of spikelet determinacy and floral organ abnormalities in rice (Oryza sativa). BMC Plant Biol. 2009;9:149 pubmed publisher
    ..These observations are consistent with miR172 functioning via translational repression or with expression of the AP2-like genes being regulated by a negative feedback loop. ..
  2. Macmillan C, Mansfield S, Stachurski Z, Evans R, Southerton S. Fasciclin-like arabinogalactan proteins: specialization for stem biomechanics and cell wall architecture in Arabidopsis and Eucalyptus. Plant J. 2010;62:689-703 pubmed publisher
    ..Our results suggest that a subset of single FAS domain FLAs contributes to plant stem strength by affecting cellulose deposition, and to the stem modulus of elasticity by affecting the integrity of the cell-wall matrix. ..