Experts and Doctors on anti bacterial agents in San Miguel de Tucumán, Tucumán, Argentina


Locale: San Miguel de Tucumán, Tucumán, Argentina
Topic: anti bacterial agents

Top Publications

  1. Delgado M, Vincent P, Farias R, Salomon R. YojI of Escherichia coli functions as a microcin J25 efflux pump. J Bacteriol. 2005;187:3465-70 pubmed
    ..The outer membrane protein TolC in addition to YojI is required for export of microcin J25 out of the cell. Microcin J25 is thus the first known substrate for YojI...
  2. de Cristóbal R, Solbiati J, Zenoff A, Vincent P, Salomon R, Yuzenkova J, et al. Microcin J25 uptake: His5 of the MccJ25 lariat ring is involved in interaction with the inner membrane MccJ25 transporter protein SbmA. J Bacteriol. 2006;188:3324-8 pubmed
    ..Our results thus suggest that MccJ25 His5 located in the lariat ring is involved, directly or indirectly, in specific interaction with SbmA and is not required for MccJ25 inhibition of RNAP. ..
  3. Delgado M, Solbiati J, Chiuchiolo M, Farias R, Salomon R. Escherichia coli outer membrane protein TolC is involved in production of the peptide antibiotic microcin J25. J Bacteriol. 1999;181:1968-70 pubmed
    ..The tolC mutants carrying multiple copies of the microcin genes were less immune to the microcin. TolC is thus likely a component of a microcin export complex containing the McjD immunity protein, an ABC exporter...
  4. de Cristóbal R, Vincent P, Salomon R. A combination of sbmA and tolC mutations in Escherichia coli K-12 Tn10-carrying strains results in hypersusceptibility to tetracycline. J Bacteriol. 2008;190:1491-4 pubmed
    ..There thus appears to be an additive effect of the mutations, resulting in almost complete suppression of the phenotypic expression of Tn10 tetracycline resistance. ..
  5. Chalon M, Bellomio A, Solbiati J, Morero R, Farias R, Vincent P. Tyrosine 9 is the key amino acid in microcin J25 superoxide overproduction. FEMS Microbiol Lett. 2009;300:90-6 pubmed publisher
    ..Only the Y9F mutant lost the ability to overproduce superoxide and inhibit oxygen consumption. The last results confirm that the Tyr(9), and not Tyr(20), is involved in the MccJ25 action on the respiratory chain target. ..
  6. Socias S, Severinov K, Salomon R. The Ile13 residue of microcin J25 is essential for recognition by the receptor FhuA, but not by the inner membrane transporter SbmA. FEMS Microbiol Lett. 2009;301:124-9 pubmed publisher
    ..From these results, we propose that the Ile(13) residue is only required for interaction with FhuA, and that VGIG is not a major recognition element by SbmA. ..