Development of a Highly Efficient Personal Sampler to collect Viable Bioaerosols

Summary

Principal Investigator: Yung-Sung Cheng
Abstract: Exposures to bioaerosols in the workplace have become a significant issue in recent years. It is essential to be able to accurately assess these potential health risks. Furthermore, because each person will react differently, it is necessary to perform such assessments on an individual basis. Workplace bioaerosols include bacteria, fungi, viruses, microbial toxins and various allergens. Numerous devices exist that are capable of collecting bioaerosols, but many are not designed for personal use. Additionally, the majority of existing devices confer a high degree of biological stress resulting in a significant loss in viability. Preservation of viability is crucial for accurate exposure assessments in that viable microorganisms pose a greater health risk. This proposal has four objectives: (1) to design and construct a personal bioaerosol sampler incorporating a re-circulating liquid cyclone collection medium, (2) to test the sampling efficiency of the proposed personal sampler in an aerosol wind tunnel for aspiration efficiency, (3) to evaluate the sampler using model bioaerosols with a focus on the effects of sampling on microbial viability, and (4) to evaluate the sampler placed on the lapel of a mannequin at different wind directions in a wind tunnel. Relevance: This research will lead to the development of a unique, highly efficient personal bioaerosol sampler capable of collecting the inhalable participate mass and retaining microbial viability. The new device will not only be beneficial in occupational settings, but may also have future potential in high risk areas such as those following any possible biological attack.
Funding Period: ----------------2007 - ---------------2011-
more information: NIH RePORT

Top Publications

  1. ncbi Evaluation of IOM personal sampler at different flow rates
    Yue Zhou
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    J Occup Environ Hyg 7:88-93. 2010
  2. ncbi Development of a personal bioaerosol sampler based on a conical cyclone with recirculating liquid film
    Alexander D Tolchinsky
    Research Center for Toxicology and Hygienic Regulation of Biopreparations, Serpukhov, Moscow, Russia
    J Occup Environ Hyg 7:156-62. 2010
  3. ncbi Personal exposure to aerosolized red tide toxins (brevetoxins)
    Yung Sung Cheng
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Occup Environ Hyg 7:326-31. 2010
  4. ncbi Evaluation of physical sampling efficiency for cyclone-based personal bioaerosol samplers in moving air environments
    Wei Chung Su
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque, NM 87108, USA
    J Environ Monit 14:2430-7. 2012
  5. ncbi A wind tunnel test of newly developed personal bioaerosol samplers
    Wei Chung Su
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    J Air Waste Manag Assoc 62:828-37. 2012
  6. ncbi Performance evaluation of two personal bioaerosol samplers
    Alexander D Tolchinsky
    Research Center for Toxicology and Hygienic Regulation of Biopreparations, Serpukchov, Moscow, Russia
    J Environ Sci Health A Tox Hazard Subst Environ Eng 46:1690-8. 2011

Detail Information

Publications6

  1. ncbi Evaluation of IOM personal sampler at different flow rates
    Yue Zhou
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    J Occup Environ Hyg 7:88-93. 2010
    ..The test results indicate that the IOM sampler can be used at higher flow rates...
  2. ncbi Development of a personal bioaerosol sampler based on a conical cyclone with recirculating liquid film
    Alexander D Tolchinsky
    Research Center for Toxicology and Hygienic Regulation of Biopreparations, Serpukhov, Moscow, Russia
    J Occup Environ Hyg 7:156-62. 2010
    ..0 x 10(6) cells per cm(3). The viability in the prototype sampler decreased to 78% after 60 min of operation...
  3. ncbi Personal exposure to aerosolized red tide toxins (brevetoxins)
    Yung Sung Cheng
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA
    J Occup Environ Hyg 7:326-31. 2010
    ..Results showed that the personal sample might provide an estimate of individual exposure level. Nasal swab samples showed that brevetoxins indeed were inhaled and deposited in the nasal passage during the March 2005 red tide event...
  4. ncbi Evaluation of physical sampling efficiency for cyclone-based personal bioaerosol samplers in moving air environments
    Wei Chung Su
    Lovelace Respiratory Research Institute, 2425 Ridgecrest Dr SE, Albuquerque, NM 87108, USA
    J Environ Monit 14:2430-7. 2012
    ..The capture efficiencies of these two samplers ranged from 70% to 80%. These data offer important information on the insight into the physical sampling characteristics of the two test samplers...
  5. ncbi A wind tunnel test of newly developed personal bioaerosol samplers
    Wei Chung Su
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico, USA
    J Air Waste Manag Assoc 62:828-37. 2012
    ..Overall, the PAS-5 is considered a better personal bioaerosol sampler than the PAS-4...
  6. ncbi Performance evaluation of two personal bioaerosol samplers
    Alexander D Tolchinsky
    Research Center for Toxicology and Hygienic Regulation of Biopreparations, Serpukchov, Moscow, Russia
    J Environ Sci Health A Tox Hazard Subst Environ Eng 46:1690-8. 2011
    ..By using an appropriate non-aqueous collection liquid, these two personal bioaerosol samplers should be able to permit continuous, long-period bioaerosol sampling with considerable viability for the captured bioaerosols...