QUALITY OF LIFE IN ADULT CANCER SURVIVORS

Summary

Principal Investigator: Charles Carver
Abstract: DESCRIPTION: (Applicant's Description) This project will examine quality of life (QOL) in adult long-term survivors of cancer (five years or more cancer-free). Given what is seen as a lack of good measures, the project's first goal is to develop a measure of QOL for this group, based on extensive interviews of long-term cancer survivors and on sound principles of test construction. After development of this measure, the second goal will be to assess QOL in a tri-ethnic (Hispanic, non-Hispanic White, and African American) sample of survivors of breast, prostate, colorectal cancers, and Hodgkin's disease, yielding information on normative experiences of long-term survivors, on possible ethnic differences, and on long-term impact of adjuvant therapies. We will also examine this group prospectively, testing factors that may influence further change in their QOL over time. Indeed, studying how differences in personality, social context, coping patterns, etc. influence long-term QOL is the project's third goal, taking advantage of the fact that we have been studying psychosocial adaptation to breast cancer for many years. Women who participated in those earlier studies completed measures of several resilience and vulnerability factors at the time of their cancer diagnosis. Now, 5 to 13 years later, we will return to these women, assess QOL, and use the measures collected earlier to prospectively predict current QOL. We will be able to examine several personal and contextual variables as prospective predictors in this way. The fact that we have this information available on large numbers of women who were treated for breast cancer also permits us to conduct a very different kind of study of survivorship. In particular, we will be able to test these variables (collected early in the cancer experience) as predictors of who survives free from cancer at particular lengths of time after treatment. The idea that psychosocial variables play a role in recurrence (or its absence) is controversial. We will examine several psychosocial variables from our data sets that are relevant as predictors of recurrence. Conducting this research at this time will allow us to make use of - and further solidify - a resource that has been years in building. There is a large cadre of survivors of breast cancer about whom we know a good deal, thanks to their earlier research involvement. These people can continue providing important information about the experience of cancer survivorship and what qualities make the process easier or harder.
Funding Period: 1998-09-01 - 2004-08-31
more information: NIH RePORT

Top Publications

  1. ncbi Perceived partner reactions to diagnosis and treatment of breast cancer: impact on psychosocial and psychosexual adjustment
    Sarah R Wimberly
    Department of Psychology, University of Miami, Coral Gables, FL 33124 2070, USA
    J Consult Clin Psychol 73:300-11. 2005
  2. ncbi Self-regulation processes and health: the importance of optimism and goal adjustment
    Heather N Rasmussen
    University of Pittsburgh, PA, USA
    J Pers 74:1721-47. 2006
  3. ncbi Relations of serotonin function to personality: current views and a key methodological issue
    Charles S Carver
    Department of Psychology, University of Miami, Coral Gables, FL 33124 0751, United States
    Psychiatry Res 144:1-15. 2006
  4. ncbi Quality of life among long-term survivors of breast cancer: Different types of antecedents predict different classes of outcomes
    Charles S Carver
    Department of Psychology, University of Miami, Coral Gables, FL 33124 0751, USA
    Psychooncology 15:749-58. 2006
  5. ncbi Enhancing adaptation during treatment and the role of individual differences
    Charles S Carver
    Department of Psychology and Sylvester Comprehensive Cancer Center, University of Miami, Coral Gables, Florida 33124 0751, USA
    Cancer 104:2602-7. 2005
  6. ncbi Impulse and constraint: perspectives from personality psychology, convergence with theory in other areas, and potential for integration
    Charles S Carver
    Department of Psychology, University of Miami, FL 33124 0751, USA
    Pers Soc Psychol Rev 9:312-33. 2005
  7. ncbi Optimistic personality and psychosocial well-being during treatment predict psychosocial well-being among long-term survivors of breast cancer
    Charles S Carver
    Department of PsychologyUniversity of Miami, Miami, FL 33124 2070, USA
    Health Psychol 24:508-16. 2005
  8. ncbi Assessing quality of life in adult cancer survivors (QLACS)
    Nancy E Avis
    Wake Forest University School of Medicine, Department of Public Health Sciences, Winston Salem, NC 27157 1063, USA
    Qual Life Res 14:1007-23. 2005
  9. ncbi A qualitative exploration of the cancer experience among long-term survivors: comparisons by cancer type, ethnicity, gender, and age
    Kristie Long Foley
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
    Psychooncology 15:248-58. 2006
  10. pmc Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors
    Nancy E Avis
    Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Health Qual Life Outcomes 4:92. 2006

Scientific Experts

Detail Information

Publications10

  1. ncbi Perceived partner reactions to diagnosis and treatment of breast cancer: impact on psychosocial and psychosexual adjustment
    Sarah R Wimberly
    Department of Psychology, University of Miami, Coral Gables, FL 33124 2070, USA
    J Consult Clin Psychol 73:300-11. 2005
    ..The pattern suggests that women's impressions of their partners' emotional involvement after surgery for breast cancer forecast their adjustment in sexual, marital, and emotional arenas over the following year...
  2. ncbi Self-regulation processes and health: the importance of optimism and goal adjustment
    Heather N Rasmussen
    University of Pittsburgh, PA, USA
    J Pers 74:1721-47. 2006
    ..Second, we present an overview of the process of disengagement from unattainable goals, focusing on recent research. We close by making recommendations for future research...
  3. ncbi Relations of serotonin function to personality: current views and a key methodological issue
    Charles S Carver
    Department of Psychology, University of Miami, Coral Gables, FL 33124 0751, United States
    Psychiatry Res 144:1-15. 2006
    ..Indeed, it is highly desirable to examine facets of each of these qualities separately...
  4. ncbi Quality of life among long-term survivors of breast cancer: Different types of antecedents predict different classes of outcomes
    Charles S Carver
    Department of Psychology, University of Miami, Coral Gables, FL 33124 0751, USA
    Psychooncology 15:749-58. 2006
    ..Financial outcomes, in contrast, were predicted by medical variables, which otherwise predicted little about long-term QOL. This divergence among aspects of QOL should receive closer attention in future work...
  5. ncbi Enhancing adaptation during treatment and the role of individual differences
    Charles S Carver
    Department of Psychology and Sylvester Comprehensive Cancer Center, University of Miami, Coral Gables, Florida 33124 0751, USA
    Cancer 104:2602-7. 2005
    ..Ongoing work is examining well being in longer term survivors, including the effects of this intervention and the possibility that the intervention will have positive consequences for physical health...
  6. ncbi Impulse and constraint: perspectives from personality psychology, convergence with theory in other areas, and potential for integration
    Charles S Carver
    Department of Psychology, University of Miami, FL 33124 0751, USA
    Pers Soc Psychol Rev 9:312-33. 2005
    ..The article closes by addressing questions raised by these ideas, including whether the issue of impulse versus constraint applies to avoidance as well as to approach...
  7. ncbi Optimistic personality and psychosocial well-being during treatment predict psychosocial well-being among long-term survivors of breast cancer
    Charles S Carver
    Department of PsychologyUniversity of Miami, Miami, FL 33124 2070, USA
    Health Psychol 24:508-16. 2005
    ..In contrast, initial medical variables played virtually no predictive role. There is substantial continuity of subjective well-being across many years among survivors of breast cancer, rooted partly in personality and social connection...
  8. ncbi Assessing quality of life in adult cancer survivors (QLACS)
    Nancy E Avis
    Wake Forest University School of Medicine, Department of Public Health Sciences, Winston Salem, NC 27157 1063, USA
    Qual Life Res 14:1007-23. 2005
    ..The new multidimensional measure has good internal consistency and validity and is appropriate for comparisons between cancer and non-cancer populations, as well as long-term follow-up of cancer patients...
  9. ncbi A qualitative exploration of the cancer experience among long-term survivors: comparisons by cancer type, ethnicity, gender, and age
    Kristie Long Foley
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
    Psychooncology 15:248-58. 2006
    ..To elucidate meanings ascribed to the cancer experience by long-term survivors...
  10. pmc Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors
    Nancy E Avis
    Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Health Qual Life Outcomes 4:92. 2006
    ..This represents an important area of study, given the large number of breast cancer patients surviving many years post diagnosis...