Designing Research Training for Rwandans in Emerging HIV &Drug Therapy


Principal Investigator: Eugene Mutimura
Abstract: DESCRIPTION (provided by applicant): Designing Research Trainings for Rwandans in Emerging HIV- and cART- associated Cardiovascular, Diabetes and Metabolic Complications Treatment program for human immunodeficiency virus (HIV) in Rwanda is highly successful, with national HIV treatment services available to 90% of the population eligible for combination antiretroviral therapy (cART). As Rwanda strives to become a middle-income country, it is undergoing rapid transition to development with increasing aging population, urbanization, potential higher rates of obesity, and will potentially be affected by two separate epidemics of non- communicable diseases and effects HIV and ART treatment. Although data are limited on metabolic, cardiovascular and diabetes complications associated with HIV infection and treatment with cART, the country's disease burden is gradually increasing due the burden of HIV- and cART- associated metabolic, cardiovascular and diabetes complications. In this planning research training program, our goal is to strengthen inter-institutional research training partnerships for our institutions of Women's Equity in Access to Care and Treatment (WE-ACTx Rwanda) (applicant institution), King Faisal Hospital, Kigali and National University of Rwanda to collaborate with Albert Einstein College of Medicine, Yeshiva University to leverage research capacity for Rwandans to address emerging HIV- and cART-associated metabolic, diabetes and cardiovascular complications including the recently described entity of "malnutrition" diabetes which is unstudied in the presence of HIV- infection and cART use. Our second goal is to enable Rwandan applicants and their Einstein collaborators to solidify relationships, assess scientific and infrastructure needs required to implement relevant research training program, identify potential trainees and the necessary staff development in Rwanda to apply and implement a successful 5-year HIV Research Training Program (HRTP) after 2- years of planning period. We envisage to carry out the following: 1) assess availability and gaps for scientific research training needs and infrastructure in Rwanda that will be required to implement the 5-year HRTP;2) carry out interactive Teleconference presentations by Einstein faculty using KFH, K Telemedicine facilities on HIV- and ART- cardiovascular, diabetes and metabolic complications;3) visit out Einstein faculty's research sites and training facilities by Rwandan trainees to study and appreciate various research training settings and programs to plan relevant research trainings for the future 5-year HRTP;4) develop an application for the 5-year HRTP that will include short-term and long-term training programs. These activities will leverage the Government of Rwanda (GoR) and Ministry of Health (MoH) mission to improve availability of, and capacity of Rwandan scientists and clinicians, and to reinforce institutional capacity. Thus, these planning grant activities will contribute to greater understanding of the requirements for research trainings to foster strong and coherent Einstein-Rwandan institutional collaborations.
Funding Period: 2013-09-20 - 2015-01-31
more information: NIH RePORT

Detail Information

Research Grants30

  1. Referral Center-Animal models of human genetic disease
    Mark E Haskins; Fiscal Year: 2013
    ..abstract_text> ..
  2. Center for Novel Therapeutics for HIV-Associated Cognitive Disorders
    Justin C McArthur; Fiscal Year: 2013
    ..5. To identify and validate surrogate biomarkers based on proteomics and lipomics. ..
  3. Research to control and eliminate malaria in SE Asia and SW Pacific
    JAMES WALTER KAZURA; Fiscal Year: 2013
    ..Synergy among the ICEMR projects and cores and incorporation ICEMR findings into national programs will help answer unresolved key issues related to malaria control and elimination locally and in the SE Asia region. ..
  4. Integrated, Home-based Treatment for MDR TB and HIV in Rural South Africa
    James C M Brust; Fiscal Year: 2013
  5. A Chiang Mai University - HMRI MRI/MRS Project: A Neurobiology Study of Methamphe
    Napapon Sailasuta; Fiscal Year: 2013
    ..These data will serve as preliminary data to develop hypothesis in the dysfunction of CNS for subsequence R01 grant application. ..
  6. Global Network for Women's and Children's Health Research
    Edward A Liechty; Fiscal Year: 2013
    ..Particular focus will be on culturally appropriate public health interventions to improve the outcome of pregnancy for women in low resource countries. ..
  7. Lifespan/Tufts/Brown Center for AIDS Research (CFAR)
    CHARLES CJ CARPENTER; Fiscal Year: 2013
    ..abstract_text> ..
  8. Notch-Mediated Expansion of Cord Blood Progenitors for Stem Cell Transplant
    Colleen Delaney; Fiscal Year: 2013
    ..Our goal is to now determine the clinical efficacy of this approach in a phase II clinical trial. ..
  9. TRIAD-2 Center for Health Disparities Research
    Debra C Wallace; Fiscal Year: 2013
    ..Thus, this is an ideal natural laboratory for disparities research. ..
    DAVID A WISE; Fiscal Year: 2013
    ..Understanding the complexities of this situation and the relationships between demographics, policy, behavior, economics, and health is the substantive aim of the Center. ..
  11. Kansas Community Cancer Health Disparities Network
    K Allen Greiner; Fiscal Year: 2013
    ..Using the building blocks already in place, our model program will reach vulnerable minorities and generate disseminable knowledge for the national CNP consortium. ..