Building Research Capacity to Improve Mental Health in China across the Lifespan


Principal Investigator: Arthur M Kleinman
Abstract: DESCRIPTION (provided by applicant): Abstract Mental disorders constitute over 14% of all disability adjusted life years in China - among the greatest for non-communicable diseases. However, most parts of China lack a basic framework for an effective mental health care system. More than 90% of persons with mental disorders and as many as 25% of persons with severe and disabling psychotic disorders never receive psychiatric care. In the past decade, China has begun to make mental disorders a new priority for the public health sector, and has begun scaling up services programs and policies, including specific attention to children, adolescents, and the elderly. A new generation of mental health reformers is deeply involved in finding ways to provide creative, recovery-oriented services and preventive interventions in very low resource settings. To date, virtually none of this work is accompanied by scientifically The overall goal of the training program is to build commitment and capacity in the Shanghai Mental Health Center and the Peking University Institute of Mental Health to conduct mental health implementation research, initiating new programs of research and training that build on more than a decade of collaboration between these institutions and the Department of Global Health and Social Medicine, Harvard Medical School. designed research able to provide genuine evaluation of such services and improve their quality. Each institute has committed 8 members to be core faculty for this program, and each institute will identify specific mental health programs to serve as core sites for research training. The program will support training of 16 PhD students in China, 8 in each institute, providing one year of intensive training in implementation research and supporting one year of PhD dissertation research linked to the identified projects. Harvard faculty will serve as mentors. In addition, this program will recruit approximately 40 6-month visiting clinical fellows over the 5 years to participate in the core research projects, creating a network of implementation researchers around China. The program will hold annual national workshops to build technical capacity for implementation research and disseminate to mental health leaders and policy makers the importance of implementation research in improving mental health services for China. The training program will be initiated with 8 senior faculty from the two Chinese institutions going to the DGHSM at Harvard in Year 1 for a intensive workshops aimed at building a curriculum for training implementation researchers. In Years 2-5, 2 junior faculty members will spend 2 months in China and 4 months in Harvard receiving advanced training, and 2 senior faculty members will go to Harvard for 1 month advanced technical training or to work on data analysis and writing. The overall goal is to develop a sustainable program of research and research training in each institution, linking research to the development of innovative mental health services for China and the region.
Funding Period: 2011-08-15 - 2016-07-31
more information: NIH RePORT

Top Publications

  1. pmc Association of MTHFR C677T polymorphism with schizophrenia and its effect on episodic memory and gray matter density in patients
    Yanling Zhang
    Institute of Mental Health, Peking University, Beijing, 100191, China
    Behav Brain Res 243:146-52. 2013

Detail Information


  1. pmc Association of MTHFR C677T polymorphism with schizophrenia and its effect on episodic memory and gray matter density in patients
    Yanling Zhang
    Institute of Mental Health, Peking University, Beijing, 100191, China
    Behav Brain Res 243:146-52. 2013
    ..Our findings suggested that the MTHFR 677T allele might have effect on risk of schizophrenia, memory impairment and GMD changes in patients...

Research Grants30

  1. Comprehensive NeuroAIDS Core Center
    Kamel Khalili; Fiscal Year: 2013
    ..abstract_text> ..
  2. Advanced Center for State Research to Scale Up EBPs for Children
    Kimberly E Hoagwood; Fiscal Year: 2013
    ..Importantly, this Center also provides an infrastructure to foster the development of new and early stage investigators by providing opportunities to engage in implementation research of high public health significance. ..
  3. Center for Substance Use and HIV/AIDS Research on Latinos in the United States
    MARIO R DE LA ROSA; Fiscal Year: 2013
  4. NCMHD Health Disparities Research Center of Excellence at Meharry
    Paul D Juarez; Fiscal Year: 2013
    ..5: To develop an administrative infrastructure that supports inter-institutional community participation in health disparities research across the three institutions. ..
  5. OUHSC Specific Pathogen Free Baboon Research Resource
    Roman F Wolf; Fiscal Year: 2013
    ..The long term objective is for the SPF baboon colony to be a stable, self-sustaining breeding colony that produces ~100 SPF baboons/year for use in NIH-funded biomedical research. ..
  6. Chronic HIV infection and Aging in NeuroAIDS (CHAIN) Center
    Howard S Fox; Fiscal Year: 2013
    ..Our goals driven by our framework: researching of the chronicity of HIV infection in the CNS with a systems biology approach. ..
  7. Early Experience, Stress and Neurobehavioral Development Center
    Megan R Gunnar; Fiscal Year: 2013
    ..Our Center also includes a cross-training program in basic developmental science and developmental psychopathology &prevention science. ..
  8. UNC-CH Nutrition Obesity Research Center
    Steven H Zeisel; Fiscal Year: 2013
    ..We measure our success as a Center by the strength of our membership, the investment in nutrition and obesity research, and the quantity and quality of publications generated by our members. ..
  9. Broadening the Investigation of Psychosis Prodrome to Different Cultural Groups
    Min Zhao; Fiscal Year: 2013
    ..Gender effects will be examined across the above aims. The study goals are consistent with the guidelines of the FOA Brain Disorders in the Developing World: Research Across the Lifespan (R21, PAR-11-031). ..
  10. Center for AIDS Research at Emory University
    James W Curran; Fiscal Year: 2013