Gene Symbol: zbtb16a
Description: zinc finger and BTB domain containing 16a
Alias: ZNF145, wu:fb93g12, wu:fc07c10, zbtb16, zgc:55675, zinc finger and BTB domain-containing protein 16-A, plzfa, promyelocytic leukemia zinc finger protein-A, zinc finger and BTB domain containing 16, zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia)
Species: zebrafish
Products:     zbtb16a

Top Publications

  1. Ozaki Y, Saito K, Shinya M, Kawasaki T, Sakai N. Evaluation of Sycp3, Plzf and Cyclin B3 expression and suitability as spermatogonia and spermatocyte markers in zebrafish. Gene Expr Patterns. 2011;11:309-15 pubmed publisher
    ..Our present data thus show that these molecules have properties that will enable their use as markers of spermatocytes and early spermatogonia in zebrafish. ..
  2. Aleksejeva E, Houel A, Briolat V, Levraud J, Langevin C, Boudinot P. Zebrafish Plzf transcription factors enhance early type I IFN response induced by two non-enveloped RNA viruses. Dev Comp Immunol. 2016;57:48-56 pubmed publisher
    ..Although zbtb16a/plzfa and zbtb16b/plzfb are not modulated by IFN produced during viral infection, their over-expression increases ..
  3. Taylor M, Hurley J, Van Epps H, Brockerhoff S. A zebrafish model for pyruvate dehydrogenase deficiency: rescue of neurological dysfunction and embryonic lethality using a ketogenic diet. Proc Natl Acad Sci U S A. 2004;101:4584-9 pubmed
    ..Our study demonstrates an approach for establishing effective therapies for PDH deficiency and other congenital diseases that affect early embryonic development. ..
  4. Sobieszczuk D, Poliakov A, Xu Q, Wilkinson D. A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation. Genes Dev. 2010;24:206-18 pubmed publisher
    ..b>plzfa is expressed widely in the neural epithelium; when overexpressed, it inhibits neurogenesis, and this inhibition is ..
  5. Gill J, Lowe L, Nguyen J, Liu P, Blake T, Venkatesh B, et al. Enforced expression of Simian virus 40 large T-antigen leads to testicular germ cell tumors in zebrafish. Zebrafish. 2010;7:333-41 pubmed publisher
    ..In addition, enforced expression of the zebrafish stem cell leukemia (scl) gene in the zebrafish testes also generated TGCTs in transgenic fish. These results demonstrate the feasibility of studying TGCTs in a model organism. ..
  6. Saito K, Siegfried K, NUSSLEIN VOLHARD C, Sakai N. Isolation and cytogenetic characterization of zebrafish meiotic prophase I mutants. Dev Dyn. 2011;240:1779-92 pubmed publisher
    ..Our results thus indicate that each responsible gene is necessary for meiotic progression during spermatogenesis and for male fertility. ..
  7. Eauclaire S, Cui S, Ma L, Matous J, Marlow F, Gupta T, et al. Mutations in vacuolar H+ -ATPase subunits lead to biliary developmental defects in zebrafish. Dev Biol. 2012;365:434-44 pubmed publisher
  8. Wong T, Collodi P. Dorsomorphin promotes survival and germline competence of zebrafish spermatogonial stem cells in culture. PLoS ONE. 2013;8:e71332 pubmed publisher
    ..Manipulation of Bmp signaling could provide a strategy to optimize culture conditions of germline stem cells from other species. ..
  9. Lin Q, Mei J, Li Z, Zhang X, Zhou L, Gui J. Distinct and Cooperative Roles of amh and dmrt1 in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish. Genetics. 2017;207:1007-1022 pubmed publisher
    ..Significantly, this study unravels novel functions of amh gene in fish. ..