xdh

Summary

Gene Symbol: xdh
Description: xanthine dehydrogenase
Alias: im:7146167, xanthine dehydrogenase/oxidase
Species: zebrafish

Top Publications

  1. Chen J, Tanguay R, Tal T, Gai Z, Ma X, Bai C, et al. Early life perfluorooctanesulphonic acid (PFOS) exposure impairs zebrafish organogenesis. Aquat Toxicol. 2014;150:124-32 pubmed publisher
    ..Taken together, early life stage exposure to PFOS perturbs various molecular pathways potentially resulting in observed defects in swim bladder and gut development. ..
  2. Ceinos R, Guillot R, Kelsh R, Cerdá Reverter J, Rotllant J. Pigment patterns in adult fish result from superimposition of two largely independent pigmentation mechanisms. Pigment Cell Melanoma Res. 2015;28:196-209 pubmed publisher
    ..These two mechanisms function largely independently, with resultant patterns superimposed to give the full pattern. ..
  3. Nord H, Dennhag N, Muck J, Von Hofsten J. Pax7 is required for establishment of the xanthophore lineage in zebrafish embryos. Mol Biol Cell. 2016;27:1853-62 pubmed publisher
    ..In summary, we propose a novel role for Pax7 in the early specification of chromatophore precursor cells. ..
  4. Vibert L, Aquino G, Gehring I, Subkankulova T, Schilling T, Rocco A, et al. An ongoing role for Wnt signaling in differentiating melanocytes in vivo. Pigment Cell Melanoma Res. 2017;30:219-232 pubmed publisher
    ..Downregulation of Wnt signaling also results in altered melanocyte morphology and organization. We conclude that Wnt signaling plays a role in regulating ongoing aspects of melanocyte differentiation in zebrafish. ..
  5. Ng A, Uribe R, Yieh L, Nuckels R, Gross J. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development. Development. 2009;136:2601-11 pubmed publisher
  6. Danilova N, Bibikova E, Covey T, Nathanson D, Dimitrova E, Konto Y, et al. The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia. Dis Model Mech. 2014;7:895-905 pubmed publisher
    ..Furthermore, the rescue of RP-deficient zebrafish with exogenous nucleosides suggests that nucleoside supplements could be beneficial in the treatment of DBA. ..
  7. Kawaguchi M, Yasumasu S, Hiroi J, Naruse K, Suzuki T, Iuchi I. Analysis of the exon-intron structures of fish, amphibian, bird and mammalian hatching enzyme genes, with special reference to the intron loss evolution of hatching enzyme genes in Teleostei. Gene. 2007;392:77-88 pubmed publisher
    ..We hypothesize that the zebrafish hatching enzyme genes were translocated from chromosome to chromosome, and lost some of their introns during evolution...
  8. Ignatius M, Moose H, El Hodiri H, Henion P. colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis. Dev Biol. 2008;313:568-83 pubmed
  9. Arduini B, Gallagher G, Henion P. Zebrafish endzone regulates neural crest-derived chromatophore differentiation and morphology. PLoS ONE. 2008;3:e2845 pubmed publisher

More Information

Publications15

  1. Zhang T, Zhou X, Ma X, Liu J. Mechanisms of cadmium-caused eye hypoplasia and hypopigmentation in zebrafish embryos. Aquat Toxicol. 2015;167:68-76 pubmed publisher
    ..Moreover, we found that compounds BIO or RA could neutralize the toxic effects of Cd. ..
  2. Budi E, Patterson L, Parichy D. Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation. Development. 2008;135:2603-14 pubmed publisher
    ..These data identify a very early, embryonic, requirement for erbb3b in the development of much later metamorphic melanophores, and suggest complex modes by which ErbB signals promote adult pigment pattern development...
  3. Arduini B, Bosse K, Henion P. Genetic ablation of neural crest cell diversification. Development. 2009;136:1987-94 pubmed publisher
    ..Our results identify a genetic regulatory pathway functionally discrete from the process of neural crest induction that is required for the initiation of neural crest cell diversification during embryonic development. ..
  4. Lee Y, Nachtrab G, Klinsawat P, Hami D, Poss K. Ras controls melanocyte expansion during zebrafish fin stripe regeneration. Dis Model Mech. 2010;3:496-503 pubmed publisher
  5. Maddirevula S, Anuppalle M, Huh T, Kim S, Rhee M. Nrdp1 governs differentiation of the melanocyte lineage via Erbb3b signaling in the zebrafish embryogenesis. Biochem Biophys Res Commun. 2011;409:454-8 pubmed publisher
  6. Cui Y, Lv S, Liu J, Nie S, Chen J, Dong Q, et al. Chronic perfluorooctanesulfonic acid exposure disrupts lipid metabolism in zebrafish. Hum Exp Toxicol. 2017;36:207-217 pubmed publisher
    ..The results indicated that lepa (leptin ?), kiss1 (kisspeptins), xdh (xanthine dehydrogenases), and insr (insulin receptor) were significantly upregulated in F1 while dgat1b (..