vtg7

Summary

Gene Symbol: vtg7
Description: vitellogenin 7
Alias: si:dkey-4c23.1, vg7, wu:fb62f05, vitellogenin 7
Species: zebrafish

Top Publications

  1. Wang H, Tan J, Emelyanov A, Korzh V, Gong Z. Hepatic and extrahepatic expression of vitellogenin genes in the zebrafish, Danio rerio. Gene. 2005;356:91-100 pubmed
    ..In situ hybridization experiments confirmed that the extrahepatic expression was actually in adipocytes associated with several organs such as the intestine, ovary, and E2-induced testis. ..
  2. Wang H, Yan T, Tan J, Gong Z. A zebrafish vitellogenin gene (vg3) encodes a novel vitellogenin without a phosvitin domain and may represent a primitive vertebrate vitellogenin gene. Gene. 2000;256:303-10 pubmed
    ..Like other vitellogenins in vertebrates, the phosvitinless vitellogenin is also synthesized mainly in the liver and weakly in the intestine. ..
  3. Finn R, Kolarevic J, Kongshaug H, Nilsen F. Evolution and differential expression of a vertebrate vitellogenin gene cluster. BMC Evol Biol. 2009;9:2 pubmed publisher
    ..The differential expression and latent neofunctionalization of vtg genes in acanthomorph teleosts is an adaptive feature associated with oocyte hydration and spawning in the marine environment. ..
  4. Lai Y, Hsieh F, Hsu T. Affinity isolation and mass spectral analysis of 1,10-phenanthroline (OP)-stimulated UV-damaged-DNA binding proteins expressed in zebrafish (Danio rerio) embryos. Fish Physiol Biochem. 2012;38:1117-1129 pubmed publisher
    ..The OP-stimulated fraction produced a much stronger UV-dependent DNA incision activity in the presence than in the absence of OP, suggesting the association of these factors with DNA damage repair under metal-deficient conditions. ..
  5. Biava P, Canaider S, Facchin F, Bianconi E, Ljungberg L, Rotilio D, et al. Stem Cell Differentiation Stage Factors from Zebrafish Embryo: A Novel Strategy to Modulate the Fate of Normal and Pathological Human (Stem) Cells. Curr Pharm Biotechnol. 2015;16:782-92 pubmed
    ..In addition we report the data not yet published about a first protein analysis of the SCDSFs and about their role in a pathological condition like neurodegeneration. ..
  6. Meng X, Bartholomew C, Craft J. Differential expression of vitellogenin and oestrogen receptor genes in the liver of zebrafish, Danio rerio. Anal Bioanal Chem. 2010;396:625-30 pubmed publisher
    ..1% of female fish), while ERbeta1 could not be detected. The very low level of expression of ERalpha in males raises questions about the accepted mechanism of oestrogenic induction of VTG in male fish. ..
  7. Connolly M, Dutkosky R, Heah T, Sayler G, Henry T. Temporal dynamics of oocyte growth and vitellogenin gene expression in zebrafish (Danio rerio). Zebrafish. 2014;11:107-14 pubmed publisher
    ..Follicular atresia among fish sampled 32 days postspawning highlights the importance of regular spawning in zebrafish and suggests that the event of spawning itself may be integral to the regulation of oocyte development. ..
  8. Eb Levadoux Y, Frelon S, Simon O, Arnaudguilhem C, Lobinski R, Mounicou S. In vivo identification of potential uranium protein targets in zebrafish ovaries after chronic waterborne exposure. Metallomics. 2017;9:525-534 pubmed publisher
    ..Potential U targets were mainly involved in three biological processes: oxidative stress regulation (SOD, GST), cytoskeleton structure (actin) and embryo early development (vtg, initiation factor). ..
  9. Babaei F, Ramalingam R, Tavendale A, Liang Y, Yan L, Ajuh P, et al. Novel blood collection method allows plasma proteome analysis from single zebrafish. J Proteome Res. 2013;12:1580-90 pubmed publisher
    ..Twenty-seven gender-dependent plasma proteins are identified and their biochemical importance discussed. Taken together, this novel technique enables analyses that were previously difficult to perform on zebrafish blood. ..

More Information

Publications20

  1. Park J, Henry T, Menn F, Compton R, Sayler G. No bioavailability of 17?-ethinylestradiol when associated with nC60 aggregates during dietary exposure in adult male zebrafish (Danio rerio). Chemosphere. 2010;81:1227-32 pubmed publisher
    ..Results have implications on the effect of nC(60) on the bioavailability of co-contaminants in organisms during dietary exposure. ..
  2. Henry T, McPherson J, Rogers E, Heah T, Hawkins S, Layton A, et al. Changes in the relative expression pattern of multiple vitellogenin genes in adult male and larval zebrafish exposed to exogenous estrogens. Comp Biochem Physiol A Mol Integr Physiol. 2009;154:119-26 pubmed publisher
    ..In larval zebrafish, the relative fold change in vtg expression varied according to specific estrogenic substance tested, but the pattern of change (i.e., Vg2A/B > Vg1A/B > VgC) was consistent for each substance that induced vtg. ..
  3. Hostelley T, Lodh S, Zaghloul N. Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes. BMC Genomics. 2016;17:318 pubmed publisher
    ..These findings provide important novel insight into shared and divergent phenotypes between two similar but distinct genetic syndromes. ..
  4. Kristoffersen B, Nerland A, Nilsen F, Kolarevic J, Finn R. Genomic and proteomic analyses reveal non-neofunctionalized vitellogenins in a basal clupeocephalan, the Atlantic herring, and point to the origin of maturational yolk proteolysis in marine teleosts. Mol Biol Evol. 2009;26:1029-44 pubmed publisher
  5. Li I, Chan C, Lu Y, Wu Y, Chen Y, Li G, et al. Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages. PLoS ONE. 2011;6:e20974 pubmed publisher
    ..Moreover, the regulation of differentiation of goblet cells in zebrafish intestine by Notch signaling at least partially mediated through Klf4a. ..
  6. Sun C, Hu L, Liu S, Gao Z, Zhang S. Functional analysis of domain of unknown function (DUF) 1943, DUF1944 and von Willebrand factor type D domain (VWD) in vitellogenin2 in zebrafish. Dev Comp Immunol. 2013;41:469-76 pubmed publisher
    ..This study also opens a new angle for identification of function of genes of unknown function, which have the domains DUF1943 and DUF1944. ..
  7. Petushkova N, Kuznetsova G, Larina O, Kisrieva Y, Samenkova N, Trifonova O, et al. One-dimensional proteomic profiling of Danio rerio embryo vitellogenin to estimate quantum dot toxicity. Proteome Sci. 2015;13:17 pubmed publisher
    ..This study demonstrates the possible utility of Vtg profiling in D. rerio embryos as a sensitive diagnostic tool to estimate nanoparticle toxicity. ..
  8. Su Y, Li L, Hou J, Wu N, Lin W, Li G. Life-cycle exposure to microcystin-LR interferes with the reproductive endocrine system of male zebrafish. Aquat Toxicol. 2016;175:205-12 pubmed publisher
  9. Zhang W, Sheng N, Wang M, Zhang H, Dai J. Zebrafish reproductive toxicity induced by chronic perfluorononanoate exposure. Aquat Toxicol. 2016;175:269-76 pubmed publisher
    ..The results of this study indicate that chronic exposure to PFNA can lead to dysfunction in the HPGL axis and sex hormone synthesis and cause adverse effects on fish reproduction. ..
  10. Baker B, Yee J, Meyer D, Yang D, Baker T. Histological and Transcriptomic Changes in Male Zebrafish Testes Due to Early Life Exposure to Low Level 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. Zebrafish. 2016;13:413-23 pubmed publisher
    ..These data will inform future investigations to elucidate the mechanism of adult-onset and transgenerational infertility due to TCDD exposure in zebrafish. ..
  11. Zheng S, Wang X, Fu J, Hu X, Xiao X, Huang L, et al. Desalting of phosphopeptides by tandem polypyrrole-c18 reverse phase micropipette tip (TMTip(PPY-C18)) based on hybrid electrostatic, ?-? stacking and hydrophobic interactions for mass spectrometric analysis. Anal Chim Acta. 2012;724:73-9 pubmed publisher
    ..Thus it provides a useful means to handle peptides that may not be detectable in acidic condition. It can be envisioned that the TMTip(PPY-C18) should be able to facilitate the exploration of large scale phosphoproteome. ..