Gene Symbol: vim
Description: vimentin
Alias: cb28, vimentin
Species: zebrafish
Products:     vim

Top Publications

  1. Kassen S, Ramanan V, Montgomery J, T Burket C, Liu C, Vihtelic T, et al. Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Dev Neurobiol. 2007;67:1009-31 pubmed
    ..Some of the Stat3-positive Müller cells expressed PCNA at 31 h, suggesting that Stat3 may play a role in signaling a subset of Müller cells to proliferate during the regeneration response. ..
  2. Sander V, Suñé G, Jopling C, Morera C, Izpisua Belmonte J. Isolation and in vitro culture of primary cardiomyocytes from adult zebrafish hearts. Nat Protoc. 2013;8:800-9 pubmed publisher
    ..Our protocol enables the study of structural and functional properties in close-to-native cardiomyocytes and allows the application of in vitro techniques and assays that are not feasible to perform in living animals. ..
  3. Aoki M, Segawa H, Naito M, Okamoto H. Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons. Biochem Biophys Res Commun. 2014;445:357-62 pubmed publisher
    ..They are not reported the involvement of axonal extension or their functions in neural cells. Finally, knockdown of these genes suggested their direct actual involvement in the extension of peripheral axons in sensory neurons. ..
  4. Chowanadisai W. Comparative genomic analysis of slc39a12/ZIP12: insight into a zinc transporter required for vertebrate nervous system development. PLoS ONE. 2014;9:e111535 pubmed publisher
    ..Consequently, the role of ZIP12 may be an important link to reported congenital malformations in numerous animal models and humans that are caused by zinc deficiency. ..
  5. LeBert D, Squirrell J, Freisinger C, Rindy J, Golenberg N, Frecentese G, et al. Damage-induced reactive oxygen species regulate vimentin and dynamic collagen-based projections to mediate wound repair. elife. 2018;7: pubmed publisher
    ..To identify mechanisms that function downstream of redox signals that modulate regeneration, a vimentin reporter of mesenchymal cells was generated by driving GFP from the vimentin promoter in zebrafish...
  6. Ganz J, Kaslin J, Hochmann S, Freudenreich D, Brand M. Heterogeneity and Fgf dependence of adult neural progenitors in the zebrafish telencephalon. Glia. 2010;58:1345-63 pubmed publisher
  7. Cui S, Leyva Vega M, Tsai E, Eauclaire S, Glessner J, Hakonarson H, et al. Evidence from human and zebrafish that GPC1 is a biliary atresia susceptibility gene. Gastroenterology. 2013;144:1107-1115.e3 pubmed publisher
    ..Based on genetic analysis of patients with BA and zebrafish, GPC1 appears to be a BA susceptibility gene. These findings also support a role for Hedgehog signaling in the pathogenesis of BA. ..
  8. Liao M, Peng W, Kan D, Chien C. Developmental pattern of the neuronal intermediate filament inaa in the zebrafish retina. J Comp Neurol. 2016;524:3810-3826 pubmed publisher
    ..In conclusion, we demonstrated the morphological features of a novel nIF, inaa, and illustrated its developmental expression pattern in the zebrafish retina. J. Comp. Neurol. 524:3810-3826, 2016. © 2016 Wiley Periodicals, Inc. ..
  9. Patra C, Kontarakis Z, Kaur H, Rayrikar A, Mukherjee D, Stainier D. The zebrafish ventricle: A hub of cardiac endothelial cells for in vitro cell behavior studies. Sci Rep. 2017;7:2687 pubmed publisher
    ..Such primary cultures will be a useful tool for supplementary in vitro studies on the accumulating zebrafish mutant lines as well as the screening of small molecule libraries on cardiac specific endothelial cells. ..

More Information


  1. Wu Y, Lou Q, Ge F, Xiong Q. Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos. Sci Rep. 2017;7:4022 pubmed publisher
  2. Eauclaire S, Cui S, Ma L, Matous J, Marlow F, Gupta T, et al. Mutations in vacuolar H+ -ATPase subunits lead to biliary developmental defects in zebrafish. Dev Biol. 2012;365:434-44 pubmed publisher
  3. Freisinger C, Huttenlocher A. Live imaging and gene expression analysis in zebrafish identifies a link between neutrophils and epithelial to mesenchymal transition. PLoS ONE. 2014;9:e112183 pubmed publisher
    ..We found that the expression of genes associated with EMT, including slug, vimentin and mmp9, are enriched in HRas(V12) transformed epithelial cells and that this enrichment requires the presence ..
  4. Goto H, Kimmey S, Row R, Matus D, Martin B. FGF and canonical Wnt signaling cooperate to induce paraxial mesoderm from tailbud neuromesodermal progenitors through regulation of a two-step epithelial to mesenchymal transition. Development. 2017;144:1412-1424 pubmed publisher
    ..Wnt signaling initiates EMT, whereas FGF signaling terminates this event. Our results indicate that germ layer induction in the zebrafish tailbud is not a simple continuation of gastrulation events. ..
  5. Tong X, Xia Z, Zu Y, Telfer H, Hu J, Yu J, et al. ngs (notochord granular surface) gene encodes a novel type of intermediate filament family protein essential for notochord maintenance in zebrafish. J Biol Chem. 2013;288:2711-20 pubmed publisher
    ..Our work sheds light on the mechanisms of notochord structural maintenance, as well as the evolution and biological function of IF family proteins. ..
  6. Kajita M, Sugimura K, Ohoka A, Burden J, Suganuma H, Ikegawa M, et al. Filamin acts as a key regulator in epithelial defence against transformed cells. Nat Commun. 2014;5:4428 pubmed publisher
    ..In this study, we demonstrate that filamin A and vimentin accumulate in normal cells specifically at the interface with Src- or RasV12-transformed cells...