Gene Symbol: vdac1
Description: voltage-dependent anion channel 1
Alias: fa13f11, wu:fa13f11, zgc:85830, voltage-dependent anion-selective channel protein 1
Damodaran S, Dlugos C, Wood T, Rabin R. Effects of chronic ethanol administration on brain protein levels: a proteomic investigation using 2-D DIGE system. Eur J Pharmacol. 2006;547:75-82 pubmed
..In the present study, we have identified some novel protein targets as well as substantiated some putative previous targets of chronic ethanol exposure. ..
Prudent J, Popgeorgiev N, Bonneau B, Thibaut J, Gadet R, Lopez J, et al
. Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish. Nat Commun. 2013;4:2330 pubmed publisher
..Thus, from an evolutionary point of view, the original function of Bcl-2 proteins might have been to contribute in controlling the global positioning system of blastomeres during gastrulation, a critical step in metazoan development. ..
Gebriel M, Prabhudesai S, Uleberg K, Larssen E, Piston D, Bjørnstad A, et al
. Zebrafish brain proteomics reveals central proteins involved in neurodegeneration. J Neurosci Res. 2014;92:104-15 pubmed publisher
Schredelseker J, Paz A, L pez C, Altenbach C, Leung C, Drexler M, et al
. High resolution structure and double electron-electron resonance of the zebrafish voltage-dependent anion channel 2 reveal an oligomeric population. J Biol Chem. 2014;289:12566-77 pubmed publisher
In recent years, there has been a vast increase in structural and functional understanding of VDAC1, but VDAC2 and -3 have been understudied despite having many unique phenotypes...
Purushothaman S, Saxena S, Meghah V, Meena Lakshmi M, Singh S, Brahmendra Swamy C, et al
. Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress. J Sleep Res. 2015;24:458-65 pubmed publisher
..It is hypothesized that the differential regulation of these genes might lead to the discovery of potential diagnostic markers for gaining insight into the light/dark-associated stress in humans. ..
Soman S, Keatinge M, Moein M, Da Costa M, Mortiboys H, Skupin A, et al
. Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1-/- zebrafish. Eur J Neurosci. 2017;45:528-535 pubmed publisher
..In contrast, genetic inactivation of the voltage dependent anion channel 1 (VDAC1), located in the outer mitochondrial membrane, did not rescue dopaminergic neurons in PINK1 deficient D. rerio...
González Durruthy M, Werhli A, Seus V, Machado K, Pazos A, Munteanu C, et al
. Decrypting Strong and Weak Single-Walled Carbon Nanotubes Interactions with Mitochondrial Voltage-Dependent Anion Channels Using Molecular Docking and Perturbation Theory. Sci Rep. 2017;7:13271 pubmed publisher
..Energy of Binding (FEB) for the interaction (nanotoxicity) between VDAC mitochondrial channels of three species (VDAC1-Mus musculus, VDAC1-Homo sapiens, VDAC2-Danio rerio) with SWCNT-H, SWCNT-OH, SWCNT-COOH carbon nanotubes...