Research Topics

Genomes and Genes

Gene Symbol: uchl5

Description: ubiquitin carboxyl-terminal hydrolase L5

Alias: wu:fj17f09, zgc:85615, ubiquitin carboxyl-terminal hydrolase isozyme L5

Species: zebrafish

Yeh H, Klesius P. Characterization and tissue expression of channel catfish (Ictalurus punctatus Rafinesque, 1818) ubiquitin carboxyl-terminal hydrolase L5 (UCHL5) cDNA. Mol Biol Rep. 2010;37:1229-34 pubmed publisher

..One enzyme involved in this process is ubiquitin carboxyl-terminal hydrolase L5 (UCHL5), which deubiquitylates the polyubiquitin chain into ubiquitin...
Manesia J, Franch M, Tabas Madrid D, Nogales Cadenas R, Vanwelden T, Van Den Bosch E, et al. Distinct Molecular Signature of Murine Fetal Liver and Adult Hematopoietic Stem Cells Identify Novel Regulators of Hematopoietic Stem Cell Function. Stem Cells Dev. 2017;26:573-584 pubmed publisher

..Our studies identified a previously unknown role for tdg, uhrf1, uchl5, and ncoa1 in the emergence of definitive hematopoiesis in zebrafish...