Gene Symbol: traf3
Description: TNF receptor-associated factor 3
Alias: zgc:92367, TNF receptor-associated factor 3
Species: zebrafish

Top Publications

  1. Wang Y, Lin C, Chuang M, Hsieh W, Lan C, Chuang Y, et al. Interspecies protein-protein interaction network construction for characterization of host-pathogen interactions: a Candida albicans-zebrafish interaction study. BMC Syst Biol. 2013;7:79 pubmed publisher
    ..With continued accumulation of interspecies transcriptomics data, the proposed method could be used to explore progressive network rewiring over time, which could benefit the development of network medicine for infectious diseases. ..
  2. He B, Yuan J, Yang L, Xie J, Weng S, Yu X, et al. The viral TRAF protein (ORF111L) from infectious spleen and kidney necrosis virus interacts with TRADD and induces caspase 8-mediated apoptosis. PLoS ONE. 2012;7:e37001 pubmed publisher
    ..This is the first report of a viral protein similar to TRAF that interacts with TRADD and induces caspase 8-mediated apoptosis, which may provide novel insights into the pathogenesis of ISKNV infection. ..
  3. Srivastava N, Shelly A, Kumar M, Pant A, Das B, Majumdar T, et al. Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish. Cell Death Discov. 2017;3:17067 pubmed publisher
    ..Inside the cytosol, A. hydrophila avoids detection by suppressing NLRs, facilitating its survival and ensuing pathogenesis. ..