Genomes and Genes
Gene Symbol: tlr9
Description: toll-like receptor 9
Alias: sb:eu392, toll-like receptor 9, TIR9
- Lee S, Peng K, Lee L, Pan C, Hour A, Her G, et al. Characterization of tilapia (Oreochromis niloticus) viperin expression, and inhibition of bacterial growth and modulation of immune-related gene expression by electrotransfer of viperin DNA into zebrafish muscle. Vet Immunol Immunopathol. 2013;151:217-28 pubmed publisher..These data indicate that such altered expression may account for the improvement in bacterial clearance following electroporation of viperin, suggesting that fish viperin has antiviral and antibacterial activities. ..
- Yeh D, Liu Y, Lo Y, Yuh C, Yu G, Lo J, et al. Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish. Proc Natl Acad Sci U S A. 2013;110:20711-6 pubmed publisher..The avian genomes lack TLR9, whereas mammalian genomes lack TLR21...
- Pietretti D, Scheer M, Fink I, Taverne N, Savelkoul H, Spaink H, et al. Identification and functional characterization of nonmammalian Toll-like receptor 20. Immunogenetics. 2014;66:123-41 pubmed publisher..In vitro stimulation of PBL with T. borreli induces an upregulation of tlr20, supportive of a role for Tlr20 in the immune response to protozoan parasites...
- Srivastava N, Shelly A, Kumar M, Pant A, Das B, Majumdar T, et al. Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish. Cell Death Discov. 2017;3:17067 pubmed publisher..Inside the cytosol, A. hydrophila avoids detection by suppressing NLRs, facilitating its survival and ensuing pathogenesis. ..
- Pan C, Wu J, Hui C, Lin C, Chen J. Insights into the antibacterial and immunomodulatory functions of the antimicrobial peptide, epinecidin-1, against Vibrio vulnificus infection in zebrafish. Fish Shellfish Immunol. 2011;31:1019-25 pubmed publisher..This study demonstrates the use of epinecidin-1 to develop inactivated material for fish bacterial infections which can provide guidelines for the future design of epinecidin-1-bacterial formulations for various in vivo applications. ..