Gene Symbol: tjp1b
Description: tight junction protein 1b
Alias: si:dkey-33l14.1, tight junction protein ZO-1, tjp1.2
McKee R, Gerlach G, Jou J, Cheng C, Wingert R. Temporal and spatial expression of tight junction genes during zebrafish pronephros development. Gene Expr Patterns. 2014;16:104-13 pubmed publisher
Kiener T, Sleptsova Friedrich I, Hunziker W. Identification, tissue distribution and developmental expression of tjp1/zo-1, tjp2/zo-2 and tjp3/zo-3 in the zebrafish, Danio rerio. Gene Expr Patterns. 2007;7:767-76 pubmed
..Interestingly, the differential tissue and developmental expression of the two tjp1 and tjp2 genes indicates that the duplicated genes have been adapted for distinct transcriptional regulations during evolution. ..
Jeong J, Kwon H, Ahn J, Kang D, Kwon S, Park J, et al
. Functional and developmental analysis of the blood-brain barrier in zebrafish. Brain Res Bull. 2008;75:619-28 pubmed publisher
Fadeev A, Krauss J, FrohnhÃ¶fer H, Irion U, NÃ¼sslein Volhard C. Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning. elife. 2015;4: pubmed publisher
..Tjp1a is a novel regulator of cell shape changes during colour pattern formation and the first cytoplasmic protein implicated in this process. ..
Dorsemans A, Soulé S, Weger M, Bourdon E, Lefebvre d Hellencourt C, Meilhac O, et al
. Impaired constitutive and regenerative neurogenesis in adult hyperglycemic zebrafish. J Comp Neurol. 2017;525:442-458 pubmed publisher
..In addition, our study reinforces the utility of zebrafish as a robust model for studying the effects of metabolic disorders on the central nervous system. J. Comp. Neurol. 525:442-458, 2017. © 2016 Wiley Periodicals, Inc. ..
Jiang C, Qin B, Liu G, Sun X, Shi H, Ding S, et al
. MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway. Oncotarget. 2016;7:52340-52353 pubmed publisher
..MiR-184 promotes RPE differentiation via inhibiting the AKT2/mTOR signaling pathway. MiR-184 based supplementary therapeutics and mTOR blocker, like rapamycin, are prospective options for AMD treatment. ..