Gene Symbol: tfap2c
Description: transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Alias: fb48g05, fb49c04, wu:fb48g05, wu:fb49c04, zgc:92088, transcription factor AP-2 gamma
Hoffman T, Javier A, Campeau S, Knight R, Schilling T. Tfap2 transcription factors in zebrafish neural crest development and ectodermal evolution. J Exp Zool B Mol Dev Evol. 2007;308:679-91 pubmed
..Here, we show that a zebrafish tfap2c is expressed in the nonneural ectoderm during early development and functions redundantly with tfap2a in NC ..
Li W, Cornell R. Redundant activities of Tfap2a and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos. Dev Biol. 2007;304:338-54 pubmed
..Here we show that zebrafish tfap2c, encoding AP-2 gamma (Tfap2c), is expressed in non-neural ectoderm including transiently in neural crest...
Rossi C, Kaji T, Artinger K. Transcriptional control of Rohon-Beard sensory neuron development at the neural plate border. Dev Dyn. 2009;238:931-43 pubmed publisher
..mRNA for neurogenin1 or dlx3b/dlx4b can rescue the lack of RBs in prdm1a mutants. Based on these data, we suggest a preliminary gene regulatory network for RB development. ..
Manohar M, Mei H, Franklin A, Sweet E, Shigaki T, Riley B, et al
. Zebrafish (Danio rerio) endomembrane antiporter similar to a yeast cation/H(+) transporter is required for neural crest development. Biochemistry. 2010;49:6557-66 pubmed publisher
..Collectively, our findings provide insights into Vnx1 function and support an unexpected role of CAX transporters in animal growth and development. ..
Kwon H, Bhat N, Sweet E, Cornell R, Riley B. Identification of early requirements for preplacodal ectoderm and sensory organ development. PLoS Genet. 2010;6:e1001133 pubmed publisher
..Initially, Bmp is required before gastrulation to co-induce four transcription factors, Tfap2a, Tfap2c, Foxi1, and Gata3, which establish preplacodal competence throughout the nonneural ectoderm...
Bhat N, Kwon H, Riley B. A gene network that coordinates preplacodal competence and neural crest specification in zebrafish. Dev Biol. 2013;373:107-17 pubmed publisher
..Low Bmp activates expression of transcription factors Tfap2a and Tfap2c in the lateral neural plate, thereby specifying neural crest fate...
Van Otterloo E, Li W, Garnett A, Cattell M, Medeiros D, Cornell R. Novel Tfap2-mediated control of soxE expression facilitated the evolutionary emergence of the neural crest. Development. 2012;139:720-30 pubmed publisher
..Together, these results show that mutations resulting in novel Tfap2-mediated regulation of sox10 and other targets contributed to the evolution of the neural crest. ..
Urbatzka R, Rocha E, Reis B, Cruzeiro C, Monteiro R, Rocha M. Effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens on steroidogenic gene expression and specific transcription factors in zebrafish. Environ Pollut. 2012;164:28-35 pubmed publisher
..Significant differences in the response of FSH?, cypa19a2, 20?-HSD were observed between EE2 and Mix. Mtf-1 and tfap2c transcription factor binding sites were discovered in the putative promoter regions and corresponding ..