Genomes and Genes
Gene Symbol: somatolactin beta
Description: somatolactin beta
Alias: slb, somatolactin beta
- Lopez M, Nica G, Motte P, Martial J, Hammerschmidt M, Muller M. Expression of the somatolactin beta gene during zebrafish embryonic development. Gene Expr Patterns. 2006;6:156-61 pubmed..In conclusion, slbeta expression defines a new, additional cell type in zebrafish pituitary that depends on pit1 and aal for its differentiation. ..
- Fukamachi S, Meyer A. Evolution of receptors for growth hormone and somatolactin in fish and land vertebrates: lessons from the lungfish and sturgeon orthologues. J Mol Evol. 2007;65:359-72 pubmed..On the basis of these results, we discuss the validity of the nomenclature of the teleost-specific copy of GHR as SLR and an ancestral receptor(s) for SL before the evolution of SLR during the FSGD. ..
- Chen M, Huang X, Yuen D, Cheng C. A study on the functional interaction between the GH/PRL family of polypeptides with their receptors in zebrafish: Evidence against GHR1 being the receptor for somatolactin. Mol Cell Endocrinol. 2011;337:114-21 pubmed publisher..The zebrafish SLs, found to be biologically active in another assay, were found to be ineffective in interacting with the zebrafish GHRs and PRLRs. Our data argue against the hypothesis that GHR1 is the SL receptor. ..
- Zhang C, Forlano P, Cone R. AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost. Cell Metab. 2012;15:256-64 pubmed publisher..This identifies the mechanism by which the central melanocortin system coordinately regulates growth and reproduction in teleosts and suggests it is an important anatomical substrate for evolutionary adaptation. ..
- Dios S, Balseiro P, Costa M, Romero A, BoltaÃ±a S, Roher N, et al. The involvement of cholesterol in sepsis and tolerance to lipopolysaccharide highlighted by the transcriptome analysis of zebrafish (Danio rerio). Zebrafish. 2014;11:421-33 pubmed publisher..Therefore, it is possible that the use of the whole animal could provide some clues to enhance the understanding of the inflammatory/tolerance response and to guide drug discovery. ..
- Wang Y, Li J, Yan Kwok A, Ge W, Leung F. A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: cloning and characterization of its tissue expression. Gen Comp Endocrinol. 2010;166:200-10 pubmed publisher..Taken together, these findings strongly suggest that a novel PRL-like protein exists in some non-mammalian vertebrates and may play an important role in target tissues, such as extra-pituitary tissues of chickens and zebrafish. ..