Gene Symbol: snai3
Description: snail family zinc finger 3
Alias: zgc:153535, zinc finger protein SNAI3, snail homolog 3
Lee H, Lo H, Lo D, Su M, Hu J, Wu C, et al
. Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos. PLoS ONE. 2015;10:e0144751 pubmed publisher
..This signaling cascade implicates the EGFR/Gsk3b/Snail axis as the molecular basis for the inhibition of cardiac valve formation by Amiodarone. ..
Manzanares M, Blanco M, Nieto M. Snail3 orthologues in vertebrates: divergent members of the Snail zinc-finger gene family. Dev Genes Evol. 2004;214:47-53 pubmed
..We further show that all three Snail genes lie in regions of extensive paralogy, revealing their common origin through segmental or chromosomal duplication. ..
Reischauer S, Levesque M, NUSSLEIN VOLHARD C, Sonawane M. Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis. PLoS Genet. 2009;5:e1000720 pubmed publisher
..Our data reveal that pen/lgl2 functions as a tumor suppressor gene in vertebrates, establishing zebrafish pen/lgl2 mutants as a valuable cancer model. ..
Liedtke D, Erhard I, Schartl M. snail gene expression in the medaka, Oryzias latipes. Gene Expr Patterns. 2011;11:181-9 pubmed publisher
..Surprisingly, no homologue of snai3 could be identified in medaka, although this gene is present in zebrafish and the puffer fishes...
Chen C, Lin D, Cheng C, Lin C, Lo Y, Yen C, et al
. Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish. Oncotarget. 2014;5:6300-11 pubmed
..Our findings and other characteristics of zebrafish, including optical clarity and small molecule treatment, provide the future utility of this model for easy and non-invasive detection and for identification of new anti-cancer drug. ..
Taylor K, Muraina I, Brethour D, Schmitt Ulms G, Nimmanon T, Ziliotto S, et al
. Zinc transporter ZIP10 forms a heteromer with ZIP6 which regulates embryonic development and cell migration. Biochem J. 2016;473:2531-44 pubmed publisher
..We postulate that a subset of ZIPs carrying prion protein (PrP)-like ectodomains, including ZIP6 and ZIP10, are integral to cellular pathways and plasticity programmes, such as EMT. ..