slc9a3.2

Summary

Gene Symbol: slc9a3.2
Description: solute carrier family 9 (sodium/hydrogen exchanger), member 3, tandem duplicate 2
Alias: nhe3b, si:dkey-3n22.6, sodium hydrogen exchanger 3b, solute carrier family 9 (sodium/hydrogen exchanger), member 3.2
Species: zebrafish

Top Publications

  1. doi Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water
    Yusuke Kumai
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 301:R1517-28. 2011
  2. doi Rhcg1 and NHE3b are involved in ammonium-dependent sodium uptake by zebrafish larvae acclimated to low-sodium water
    Tin Han Shih
    Department of Life Science, National Taiwan Normal University, Taipei, Taiwan
    Am J Physiol Regul Integr Comp Physiol 302:R84-93. 2012
  3. ncbi Gene expression of Na+/H+ exchanger in zebrafish H+ -ATPase-rich cells during acclimation to low-Na+ and acidic environments
    Jia Jiun Yan
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan, ROC
    Am J Physiol Cell Physiol 293:C1814-23. 2007
  4. doi Carbonic anhydrase 2-like a and 15a are involved in acid-base regulation and Na+ uptake in zebrafish H+-ATPase-rich cells
    Tzung Yi Lin
    Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
    Am J Physiol Cell Physiol 294:C1250-60. 2008
  5. doi Role of SLC12A10.2, a Na-Cl cotransporter-like protein, in a Cl uptake mechanism in zebrafish (Danio rerio)
    Yi Fang Wang
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan 11529, ROC
    Am J Physiol Regul Integr Comp Physiol 296:R1650-60. 2009
  6. doi Expression regulation of Na+-K+-ATPase alpha1-subunit subtypes in zebrafish gill ionocytes
    Bo Kai Liao
    Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
    Am J Physiol Regul Integr Comp Physiol 296:R1897-906. 2009
  7. doi Cortisol regulates Na+ uptake in zebrafish, Danio rerio, larvae via the glucocorticoid receptor
    Yusuke Kumai
    Department of Biology, University of Ottawa, Ottawa, ON, Canada
    Mol Cell Endocrinol 364:113-25. 2012
  8. doi Cortisol promotes differentiation of epidermal ionocytes through Foxi3 transcription factors in zebrafish (Danio rerio)
    Shelly Abad Cruz
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan, ROC
    Comp Biochem Physiol A Mol Integr Physiol 164:249-57. 2013
  9. pmc The tight junction protein claudin-b regulates epithelial permeability and sodium handling in larval zebrafish, Danio rerio
    Raymond W M Kwong
    Department of Biology, University of Ottawa, 30 Marie Curie, Ottawa, Ontario, K1N 10 6N5 Canada
    Am J Physiol Regul Integr Comp Physiol 304:R504-13. 2013
  10. pmc Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill
    Jason P Breves
    Department of Biology, Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA 01003, USA
    Mol Cell Endocrinol 369:98-106. 2013

Scientific Experts

  • Raymond W M Kwong
  • Pung Pung Hwang
  • Yusuke Kumai
  • Jia Jiun Yan
  • Ming Yi Chou
  • Bo Kai Liao
  • Shelly Abad Cruz
  • Daniela Volcan Almeida
  • Yusuke Ito
  • Jason P Breves
  • Tin Han Shih
  • Steve F Perry
  • Jiun Lin Horng
  • Yi Fang Wang
  • Tzung Yi Lin
  • Stephen D McCormick
  • Camila De Martinez Gaspar Martins
  • Márcio de Azevedo Figueiredo
  • Sandy B Serizier
  • Sayako Kobayashi
  • Luis Fernando Marins
  • Carlos Frederico Ceccon Lanes
  • Hisako Miyagi
  • Masahiro Esaki
  • Rolf O Karlstrom
  • Kazuyuki Hoshijima
  • Shigehisa Hirose
  • Adalto Bianchini
  • Vincent Goffin
  • Nobuhiro Nakamura
  • Pei Lin Chao
  • Sian Tai Liu
  • Mathilakath M Vijayan
  • Dinushan Nesan
  • Li Yih Lin
  • Liang Chun Wu
  • Sheng Ping L Hwang
  • Jo Chi Hung
  • Yung Che Tseng
  • Ruo Dong Chen
  • Junya Hiroi
  • Chung Der Hsiao
  • Toyoji Kaneko

Detail Information

Publications14

  1. doi Ammonia excretion via Rhcg1 facilitates Na⁺ uptake in larval zebrafish, Danio rerio, in acidic water
    Yusuke Kumai
    Department of Biology, University of Ottawa, Ottawa, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 301:R1517-28. 2011
    ..0). A role for NHE in Na(+) uptake was further confirmed by translational knockdown of NHE3b, an isoform of NHE thought to be responsible for Na(+)/H(+) exchange in zebrafish larvae...
  2. doi Rhcg1 and NHE3b are involved in ammonium-dependent sodium uptake by zebrafish larvae acclimated to low-sodium water
    Tin Han Shih
    Department of Life Science, National Taiwan Normal University, Taipei, Taiwan
    Am J Physiol Regul Integr Comp Physiol 302:R84-93. 2012
    ..Knockdown of nhe3b translation or inhibitor (5-ethylisopropyl amiloride) treatment also decreased both the NH4(+) excretion and Na(+) ..
  3. ncbi Gene expression of Na+/H+ exchanger in zebrafish H+ -ATPase-rich cells during acclimation to low-Na+ and acidic environments
    Jia Jiun Yan
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan, ROC
    Am J Physiol Cell Physiol 293:C1814-23. 2007
    ..By RT-PCR analysis and double/triple in situ hybridization/immunocytochemistry, only zebrafish NHE3b was expressed in zebrafish gills and was colocalized with V-H(+)-ATPase but not with Na(+)-K(+)-ATPase, indicating ..
  4. doi Carbonic anhydrase 2-like a and 15a are involved in acid-base regulation and Na+ uptake in zebrafish H+-ATPase-rich cells
    Tzung Yi Lin
    Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
    Am J Physiol Cell Physiol 294:C1250-60. 2008
    ..These results provide molecular physiological evidence to support the roles of these two zCA isoforms in Na+ uptake and acid-base regulation mechanisms in zebrafish HR cells...
  5. doi Role of SLC12A10.2, a Na-Cl cotransporter-like protein, in a Cl uptake mechanism in zebrafish (Danio rerio)
    Yi Fang Wang
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan 11529, ROC
    Am J Physiol Regul Integr Comp Physiol 296:R1650-60. 2009
    ..These results for the first time provide in vivo molecular physiological evidence for the possible role of the NCC in the Cl(-) uptake mechanism in zebrafish skin/gills...
  6. doi Expression regulation of Na+-K+-ATPase alpha1-subunit subtypes in zebrafish gill ionocytes
    Bo Kai Liao
    Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan
    Am J Physiol Regul Integr Comp Physiol 296:R1897-906. 2009
    ..Taken together, zATP1a1a.1, zATP1a1a.2, and zATP1a1a.5 may provide driving force for Na+-coupled cotransporter activity specifically in NaR, NCC, and HR cells, respectively...
  7. doi Cortisol regulates Na+ uptake in zebrafish, Danio rerio, larvae via the glucocorticoid receptor
    Yusuke Kumai
    Department of Biology, University of Ottawa, Ottawa, ON, Canada
    Mol Cell Endocrinol 364:113-25. 2012
    ..Knockdown of Rhcg1, an apical membrane ammonia channel or Na(+)/H(+) exchanger 3b (NHE3b), proteins known to play an important role in facilitating Na(+) uptake in acidic water, prevented the stimulatory ..
  8. doi Cortisol promotes differentiation of epidermal ionocytes through Foxi3 transcription factors in zebrafish (Danio rerio)
    Shelly Abad Cruz
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan, ROC
    Comp Biochem Physiol A Mol Integr Physiol 164:249-57. 2013
    ..We conclude that foxi3a/b transactivation by cortisol-GR favors differentiation of ionocyte progenitors, thereby facilitating proliferation of mature ionocytes...
  9. pmc The tight junction protein claudin-b regulates epithelial permeability and sodium handling in larval zebrafish, Danio rerio
    Raymond W M Kwong
    Department of Biology, University of Ottawa, 30 Marie Curie, Ottawa, Ontario, K1N 10 6N5 Canada
    Am J Physiol Regul Integr Comp Physiol 304:R504-13. 2013
    ..Overall, the results suggest that claudin-b plays an important role in regulating epithelial permeability and Na(+) handling in zebrafish...
  10. pmc Prolactin regulates transcription of the ion uptake Na+/Cl- cotransporter (ncc) gene in zebrafish gill
    Jason P Breves
    Department of Biology, Center for Neuroendocrine Studies, University of Massachusetts, Amherst, MA 01003, USA
    Mol Cell Endocrinol 369:98-106. 2013
    ..2), Na(+)/H(+) exchanger (nhe3b; slc9a3.2), and epithelial Ca(2+) channel (ecac; trpv6) transcripts within the gill...
  11. pmc Close Association of Carbonic Anhydrase (CA2a and CA15a), Na(+)/H(+) Exchanger (Nhe3b), and Ammonia Transporter Rhcg1 in Zebrafish Ionocytes Responsible for Na(+) Uptake
    Yusuke Ito
    Department of Biological Sciences, Tokyo Institute of Technology Yokohama, Japan
    Front Physiol 4:59. 2013
    ..An in situ proximity ligation assay demonstrated a very close association of CA2a, CA15a, Na(+)/H(+) exchanger 3b (Nhe3b), and Rhcg1 ammonia transporter in H-MRC...
  12. doi Growth hormone transgenesis affects osmoregulation and energy metabolism in zebrafish (Danio rerio)
    Daniela Volcan Almeida
    Programa de Pós Graduação em Ciências Fisiológicas Fisiologia Animal Comparada, Instituto de Ciencias Biologicas, Universidade Federal do Rio Grande, FURG, Rio Grande, Av Italia, Km 8, Rio Grande, RS, 96201 900, Brazil
    Transgenic Res 22:75-88. 2013
    ....
  13. pmc Isotocin controls ion regulation through regulating ionocyte progenitor differentiation and proliferation
    Ming Yi Chou
    Institute of Cellular and Organismic Biology, Academia Sinica, Nankang, Taipei, Taiwan
    Cell Mol Life Sci 68:2797-809. 2011
    ....