Gene Symbol: slc18a3b
Description: solute carrier family 18 (vesicular acetylcholine transporter), member 3b
Alias: Slc18a3, VAChT-B, zgc:64220, VAChT, solute carrier family 18 (vesicular acetylcholine), member 3b, solute carrier family 18 member 3, solute carrier family 18 member 3-B, vachtb, vchat, vesicular acetylcholine transporter b, zSlc18a3
Hong E, Santhakumar K, Akitake C, Ahn S, Thisse C, Thisse B, et al
. Cholinergic left-right asymmetry in the habenulo-interpeduncular pathway. Proc Natl Acad Sci U S A. 2013;110:21171-6 pubmed publisher
..Our studies of the newly identified cholinergic gene locus resolve the neurotransmitter identity of the zebrafish habenular nuclei and reveal functional asymmetry in a major cholinergic neuromodulatory pathway of the vertebrate brain. ..
Jacobsson J, Stephansson O, Fredriksson R. C6ORF192 forms a unique evolutionary branch among solute carriers (SLC16, SLC17, and SLC18) and is abundantly expressed in several brain regions. J Mol Neurosci. 2010;41:230-42 pubmed publisher
..Expression profiling by quantitative real-time polymerase chain reaction and in situ hybridization showed that C6ORF192 transcript can be detected in several tissues, both in the central nervous system and the periphery. ..
deCarvalho T, Subedi A, Rock J, Harfe B, Thisse C, Thisse B, et al
. Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish. Genesis. 2014;52:636-55 pubmed publisher
..Although many aspects of habenular organization appear conserved with rodents, the zebrafish habenulae also possess unique properties that may underlie lateralization of their functions. ..
Lerebours A, Gonzalez P, Adam C, Camilleri V, Bourdineaud J, Garnier Laplace J. Comparative analysis of gene expression in brain, liver, skeletal muscles, and gills of zebrafish (Danio rerio) exposed to environmentally relevant waterborne uranium concentrations. Environ Toxicol Chem. 2009;28:1271-8 pubmed publisher
..During the depuration phase, uranium excretion was inefficient in brain and skeletal muscles, and expression of most of the tissue-specific genes was repressed or unchanged. ..
HÃ¼sken U, Stickney H, Gestri G, Bianco I, Faro A, Young R, et al
. Tcf7l2 is required for left-right asymmetric differentiation of habenular neurons. Curr Biol. 2014;24:2217-27 pubmed publisher
..Tcf7l2 is essential for lateralized fate selection by habenular neurons that can differentiate along two alternative pathways, thereby leading to major neural circuit asymmetries. ..
Quan F, Dubessy C, Galant S, Kenigfest N, Djenoune L, Leprince J, et al
. Comparative distribution and in vitro activities of the urotensin II-related peptides URP1 and URP2 in zebrafish: evidence for their colocalization in spinal cerebrospinal fluid-contacting neurons. PLoS ONE. 2015;10:e0119290 pubmed publisher
..44 and 8.61, respectively). The functional redundancy of URP1 and URP2 as well as the colocalization of their mRNAs in the spinal cord suggest the robustness of this peptidic system and its physiological importance in zebrafish. ..