Gene Symbol: selenon
Description: selenoprotein N
Alias: SePN, cb686, selN, sepn1, wu:fb06g01, wu:fb73d02, wu:fv41b08, zgc:101091, selenoprotein N, selenoprotein N, 1
Deniziak M, Thisse C, Rederstorff M, Hindelang C, Thisse B, Lescure A. Loss of selenoprotein N function causes disruption of muscle architecture in the zebrafish embryo. Exp Cell Res. 2007;313:156-67 pubmed
Mutations in the gene coding for selenoprotein N (SelN), a selenium containing protein of unknown function, cause different forms of congenital muscular dystrophy in humans...
Sun Q, Kirnarsky L, Sherman S, Gladyshev V. Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems. Proc Natl Acad Sci U S A. 2001;98:3673-8 pubmed
Thisse C, Degrave A, Kryukov G, Gladyshev V, Obrecht Pflumio S, Krol A, et al
. Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish. Gene Expr Patterns. 2003;3:525-32 pubmed
..Therefore, tissue- and development-specific expression patterns provided new information for selenoproteins of unknown function. ..
Wang K, Ma J, He M, Gao G, Xu H, Sang J, et al
. Toxicity assessments of near-infrared upconversion luminescent LaF3:Yb,Er in early development of zebrafish embryos. Theranostics. 2013;3:258-66 pubmed publisher
..In conclusion, the exploration of LaF3:Yb,Er for in vivo applications in animals and humans must consider UCNPs biocompatibility. ..
Howard M, Aggarwal G, Anderson C, Khatri S, Flanigan K, Atkins J. Recoding elements located adjacent to a subset of eukaryal selenocysteine-specifying UGA codons. EMBO J. 2005;24:1596-607 pubmed
..stop codon redefinition element located adjacent to a selenocysteine-encoding UGA codon in the eukaryal gene, SEPN1. This element is sufficient to stimulate high-level (6%) translational redefinition of the SEPN1 UGA codon in ..
Jurynec M, Xia R, Mackrill J, Gunther D, Crawford T, Flanigan K, et al
. Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle. Proc Natl Acad Sci U S A. 2008;105:12485-90 pubmed publisher
Mutations affecting the seemingly unrelated gene products, SepN1, a selenoprotein of unknown function, and RyR1, the major component of the ryanodine receptor intracellular calcium release channel, result in an overlapping spectrum of ..