sec63

Summary

Gene Symbol: sec63
Description: SEC63 homolog, protein translocation regulator
Alias: SEC63-like, zgc:92718, translocation protein SEC63 homolog
Species: zebrafish
Products:     sec63

Top Publications

  1. Monk K, Voas M, Franzini Armstrong C, Hakkinen I, Talbot W. Mutation of sec63 in zebrafish causes defects in myelinated axons and liver pathology. Dis Model Mech. 2013;6:135-45 pubmed publisher
    Mutations in SEC63 cause polycystic liver disease in humans. Sec63 is a member of the endoplasmic reticulum (ER) translocon machinery, although it is unclear how mutations in SEC63 lead to liver cyst formation in humans...
  2. Tietz Bogert P, Huang B, Gradilone S, Masyuk T, Moulder G, Ekker S, et al. The zebrafish as a model to study polycystic liver disease. Zebrafish. 2013;10:211-7 pubmed publisher
    ..In this study, we employed zebrafish injected with morpholinos against genes involved in the PLD, including sec63, prkcsh, and pkd1a...