Gene Symbol: sdc3
Description: syndecan 3
Alias: wu:fa97a01, syndecan-3
Lambaerts K, Van Dyck S, Mortier E, Ivarsson Y, Degeest G, Luyten A, et al
. Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish. J Cell Sci. 2012;125:1129-40 pubmed publisher
..This study identifies the importance of the syntenin-syndecan-PIP2-Arf6 complex for the progression of fish epiboly and establishes its key role in directional cell movements during early development. ..
Hofmeister W, Devine C, Key B. Distinct expression patterns of syndecans in the embryonic zebrafish brain. Gene Expr Patterns. 2013;13:126-32 pubmed publisher
..These genes show differing expression patterns in the brain which provides putative insights into their functional specificity. ..
Venero Galanternik M, Kramer K, Piotrowski T. Heparan Sulfate Proteoglycans Regulate Fgf Signaling and Cell Polarity during Collective Cell Migration. Cell Rep. 2015;: pubmed publisher
..The HSPGs themselves are regulated by the Wnt/Î²-catenin and Fgf pathways and thus are integral components of the regulatory network that coordinates collective cell migration with organ specification and morphogenesis. ..
Venero Galanternik M, Lush M, Piotrowski T. Glypican4 modulates lateral line collective cell migration non cell-autonomously. Dev Biol. 2016;419:321-335 pubmed publisher
..Our results show that glypican4 has distinct functions in primordium cells and cells in the environment and that both of these functions are essential for collective cell migration. ..
Müller Deile J, Gellrich F, Schenk H, Schroder P, Nyström J, Lorenzen J, et al
. Overexpression of TGF-? Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans. Cell Physiol Biochem. 2016;40:819-830 pubmed
..We found that syndecan 1 and 4 were predominantly expressed in podocytes while syndecan 3 was largely expressed in glomerular endothelial cells. Versican could be detected in both cell types...