Gene Symbol: sall4
Description: spalt-like transcription factor 4
Alias: cb614, ik:tdsubc_2c1, sb:cb372, sb:cb614, wu:fa01g03, xx:tdsubc_2c1, sal-like protein 4, cb372, sal-like 4
Harvey S, Logan M. sall4 acts downstream of tbx5 and is required for pectoral fin outgrowth. Development. 2006;133:1165-73 pubmed
..defined by forelimb defects associated with the eye disorder Duane anomaly and results from mutations in the gene SALL4. Forelimb defects in individuals with OS range from subtle thumb abnormalities to truncated limbs...
Jackson R, Braubach O, Bilkey J, Zhang J, Akimenko M, Fine A, et al
. Expression of sall4 in taste buds of zebrafish. Dev Neurobiol. 2013;73:543-58 pubmed publisher
We characterized the expression of sall4, a gene encoding a zinc finger transcription factor involved in the maintenance of embryonic stem cells, in taste buds of zebrafish (Danio rerio)...
McDermott B, Baucom J, Hudspeth A. Analysis and functional evaluation of the hair-cell transcriptome. Proc Natl Acad Sci U S A. 2007;104:11820-5 pubmed
..Moreover, a search for candidate genes that underlie heritable deafness identified a human ortholog of a zebrafish hair-cell gene whose map location is bracketed by the markers of a deafness locus. ..
Christen B, Robles V, Raya M, Paramonov I, Izpisua Belmonte J. Regeneration and reprogramming compared. BMC Biol. 2010;8:5 pubmed publisher
..We found that some of the pluripotency associated factors (oct4/pou5f1, sox2, c-myc, klf4, tert, sall4, zic3, dppa2/4 and fut1, a homologue of ssea1) were expressed before and during regeneration and that at least two ..
Robles V, Marti M, Izpisua Belmonte J. Study of pluripotency markers in zebrafish embryos and transient embryonic stem cell cultures. Zebrafish. 2011;8:57-63 pubmed publisher
..We consider this study a step forward in the knowledge of zebrafish pluripotency markers and, therefore, an important tool for the monitoring of zebrafish embryonic cell cultures. ..
Paik E, Mahony S, White R, Price E, DiBiase A, Dorjsuren B, et al
. A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis. Stem Cell Reports. 2013;1:425-36 pubmed publisher
..combined with gene-expression profiling in zebrafish, and identified the transcription factor spalt-like 4 (sall4) as a Cdx4 target. ChIP-seq revealed that Sall4 bound to its own gene locus and the cdx4 locus...
Dong X, Li J, He L, Gu C, Jia W, Yue Y, et al
. Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes. J Biol Chem. 2017;292:13045-13055 pubmed publisher
..Additionally, knocking down znfl1s causes the reduced expression of sall4, a direct regulator of pou5f3, in the posterior neuroectoderm, and overexpression of sall4 ..
Lin C, He J, Zeng C, Loo M, Chang W, Zhang P, et al
. microRNA-206 modulates an Rtn4a/Cxcr4a/Thbs3a axis in newly forming somites to maintain and stabilize the somite boundary formation of zebrafish embryos. Open Biol. 2017;7: pubmed publisher
..Collectively, we suggest that miR-206 mediates a novel pathway, the Rtn4a/Cxcr4a/Thbs3a axis, that allows boundary cells to undergo MET and form somite boundaries in the newly forming somites of zebrafish embryos. ..
Aanes H, Østrup O, Andersen I, Moen L, Mathavan S, Collas P, et al
. Differential transcript isoform usage pre- and post-zygotic genome activation in zebrafish. BMC Genomics. 2013;14:331 pubmed publisher
..New isoforms are identified even for well-characterized genes such as pou5f1, sall4 and dnmt1...