rrm2b

Summary

Gene Symbol: rrm2b
Description: ribonucleotide reductase M2 b
Alias: fb72h01, fb93b05, rrm2, si:zc215i13.5, wu:fb72h01, wu:fb93b05, ribonucleoside-diphosphate reductase subunit M2 B
Species: zebrafish

Top Publications

  1. Li Z, Long Y, Zhong L, Song G, Zhang X, Yuan L, et al. RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate. J Appl Toxicol. 2016;36:94-104 pubmed publisher
    ..These results provide insight into the genome-wide response of ZF4 cells following exposure to MMS, and this knowledge will inform future toxicogenomic data analysis and environmental health risk assessment. ..
  2. Song Y, Shi Y, Carland T, Lian S, Sasaki T, Schork N, et al. p53-Dependent DNA damage response sensitive to editing-defective tRNA synthetase in zebrafish. Proc Natl Acad Sci U S A. 2016;113:8460-5 pubmed publisher
    ..We suggest that the sensitivity of p53 to expression of an editing-defective tRNA synthetase has a critical role in promoting genome integrity and organismal homeostasis. ..
  3. Shang H, Li Q, Feng G, Cui Z. Molecular analysis and functions of p53R2 in zebrafish. Gene. 2011;475:30-8 pubmed publisher
    ..Therefore, functions of p53R2 in zebrafish are closely associated with its activity in DNA repair and synthesis. ..
  4. Shang H, Li Q, Feng G, Cui Z. Identification and characterization of alternative promoters, transcripts and protein isoforms of zebrafish R2 gene. PLoS ONE. 2011;6:e24089 pubmed publisher
    ..Thus, our results suggest that multilayered mechanisms control the differential expression and function of zebrafish R2 gene during cell cycle and under genotoxic stress. ..
  5. Balci T, Prykhozhij S, Teh E, Da as S, McBride E, Liwski R, et al. A transgenic zebrafish model expressing KIT-D816V recapitulates features of aggressive systemic mastocytosis. Br J Haematol. 2014;167:48-61 pubmed publisher
    ..This study represents the first zebrafish model of a mast cell disease with an aggressive adult phenotype and embryonic markers that could be exploited to screen for novel agents in SM. ..