rpl8

Summary

Gene Symbol: rpl8
Description: ribosomal protein L8
Alias: zgc:73105, zgc:77641, 60S ribosomal protein L8
Species: zebrafish
Products:     rpl8

Top Publications

  1. Yu L, Deng J, Shi X, Liu C, Yu K, Zhou B. Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamic-pituitary-thyroid axis of zebrafish larvae. Aquat Toxicol. 2010;97:226-33 pubmed publisher
  2. Wang Q, Liang K, Liu J, Yang L, Guo Y, Liu C, et al. Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquat Toxicol. 2013;126:207-13 pubmed publisher
  3. van Aerle R, Kille P, Lange A, Tyler C. Evidence for the existence of a functional Kiss1/Kiss1 receptor pathway in fish. Peptides. 2008;29:57-64 pubmed
    ..This is the first report of the existence and characterization of the Kiss1 gene outside the mammalian taxa, suggesting that a functional Kiss1/Kiss1 receptor pathway is conserved across vertebrate species. ..
  4. Han Z, Li Y, Zhang S, Song N, Xu H, Dang Y, et al. Prenatal transfer of decabromodiphenyl ether (BDE-209) results in disruption of the thyroid system and developmental toxicity in zebrafish offspring. Aquat Toxicol. 2017;190:46-52 pubmed publisher
    ..These results suggest that exposure of parent zebrafish to BDE-209 can cause developmental toxicity in offspring and disruption of the thyroid endocrine system of offspring. ..
  5. Zhu Y, Su G, Yang D, Zhang Y, Yu L, Li Y, et al. Time-dependent inhibitory effects of Tris(1, 3-dichloro-2-propyl) phosphate on growth and transcription of genes involved in the GH/IGF axis, but not the HPT axis, in female zebrafish. Environ Pollut. 2017;229:470-478 pubmed publisher
  6. Akerberg A, Henner A, Stewart S, Stankunas K. Histone demethylases Kdm6ba and Kdm6bb redundantly promote cardiomyocyte proliferation during zebrafish heart ventricle maturation. Dev Biol. 2017;426:84-96 pubmed publisher
    ..Our results indicate a restricted and likely locus-specific role for Kdm6b demethylases during heart ventricle maturation rather than initial cardiogenesis. ..
  7. Huang G, Tian X, Fang X, Ji F. Waterborne exposure to bisphenol F causes thyroid endocrine disruption in zebrafish larvae. Chemosphere. 2016;147:188-94 pubmed publisher
  8. Jeffries M, Stultz A, Smith A, Stephens D, Rawlings J, Belanger S, et al. The fish embryo toxicity test as a replacement for the larval growth and survival test: A comparison of test sensitivity and identification of alternative endpoints in zebrafish and fathead minnows. Environ Toxicol Chem. 2015;34:1369-81 pubmed publisher
    ..The results not only show the utility of the fathead minnow FET test as a replacement for the LGS test but also provide evidence that inclusion of additional endpoints could improve the predictive power of the FET test. ..
  9. Uren Webster T, Laing L, Florance H, Santos E. Effects of glyphosate and its formulation, roundup, on reproduction in zebrafish (Danio rerio). Environ Sci Technol. 2014;48:1271-9 pubmed publisher

More Information

Publications28

  1. Chen Q, Yu L, Yang L, Zhou B. Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae. Aquat Toxicol. 2012;110-111:141-8 pubmed publisher
    ..These results suggest that the hypothalamic-pituitary-thyroid axis can be evaluated to determine thyroid endocrine disruption by BDE-209 in developing zebrafish larvae. ..
  2. Rissone A, Foglia E, Sangiorgio L, Cermenati S, Nicoli S, Cimbro S, et al. The synaptic proteins ?-neurexin and neuroligin synergize with extracellular matrix-binding vascular endothelial growth factor a during zebrafish vascular development. Arterioscler Thromb Vasc Biol. 2012;32:1563-72 pubmed publisher
    ..Our data represent the first in vivo evidence of the role of neurexin and neuroligin in embryonic blood vessel formation and provide insights into their mechanism of action. ..
  3. Yu L, Zhao G, Feng M, Wen W, Li K, Zhang P, et al. Chronic exposure to pentachlorophenol alters thyroid hormones and thyroid hormone pathway mRNAs in zebrafish. Environ Toxicol Chem. 2014;33:170-6 pubmed publisher
  4. Urbatzka R, Rocha E, Reis B, Cruzeiro C, Monteiro R, Rocha M. Effects of ethinylestradiol and of an environmentally relevant mixture of xenoestrogens on steroidogenic gene expression and specific transcription factors in zebrafish. Environ Pollut. 2012;164:28-35 pubmed publisher
    ..The results suggest that "non-classical effects" of estrogenic EDC in fish are mediated via transcription factors. ..
  5. Wang X, Yang L, Wang Q, Guo Y, Li N, Ma M, et al. The neurotoxicity of DE-71: effects on neural development and impairment of serotonergic signaling in zebrafish larvae. J Appl Toxicol. 2016;36:1605-1613 pubmed publisher
    ..Copyright © 2016 John Wiley & Sons, Ltd. ..
  6. Shi X, Zhou B. The role of Nrf2 and MAPK pathways in PFOS-induced oxidative stress in zebrafish embryos. Toxicol Sci. 2010;115:391-400 pubmed publisher
    ..Furthermore, we showed that morpholino-mediated knockdown of Nrf2 reduced PFOS-induced HO-1 gene expression. These findings demonstrate that Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae. ..
  7. Armstrong B, Henner A, Stewart S, Stankunas K. Shh promotes direct interactions between epidermal cells and osteoblast progenitors to shape regenerated zebrafish bone. Development. 2017;144:1165-1176 pubmed publisher
    ..Progressively separated pObs pools then continue regenerating independently to collectively re-form a now branched skeletal structure. ..
  8. Macaulay L, Chernick M, Chen A, Hinton D, Bailey J, Kullman S, et al. Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development. Environ Toxicol Chem. 2017;36:36-48 pubmed publisher
    ..Overall, these results indicate that exposures to PBDE/OH-BDE mixtures adversely impact zebrafish maturation during metamorphosis. Environ Toxicol Chem 2017;36:36-48. © 2016 SETAC. ..
  9. Jia P, Ma Y, Lu C, Mirza Z, Zhang W, Jia Y, et al. The Effects of Disturbance on Hypothalamus-Pituitary-Thyroid (HPT) Axis in Zebrafish Larvae after Exposure to DEHP. PLoS ONE. 2016;11:e0155762 pubmed publisher
  10. Chen L, Zhu B, Guo Y, Xu T, Lee J, Qian P, et al. High-throughput transcriptome sequencing reveals the combined effects of key e-waste contaminants, decabromodiphenyl ether (BDE-209) and lead, in zebrafish larvae. Environ Pollut. 2016;214:324-333 pubmed publisher
    ..Overall, the interaction between BDE-209 and Pb led to synergistic and antagonistic effects on gene transcriptions, with concerted contribution from their individual toxicological properties. ..
  11. Uren Webster T, Lewis C, Filby A, Paull G, Santos E. Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish. Aquat Toxicol. 2010;99:360-9 pubmed publisher
  12. Wang Q, Lam J, Man Y, Lai N, Kwok K, Guo Y, et al. Bioconcentration, metabolism and neurotoxicity of the organophorous flame retardant 1,3-dichloro 2-propyl phosphate (TDCPP) to zebrafish. Aquat Toxicol. 2015;158:108-15 pubmed publisher
    ..Our results showed that females are more sensitive to TDCPP stress than males in terms of TDCPP-induced neurotoxicity. We demonstrate that long-term exposure to lower concentrations of TDCPP in fish can lead to neurotoxicity. ..
  13. Zhai W, Huang Z, Chen L, Feng C, Li B, Li T. Thyroid endocrine disruption in zebrafish larvae after exposure to mono-(2-ethylhexyl) phthalate (MEHP). PLoS ONE. 2014;9:e92465 pubmed publisher
  14. Deng J, Liu C, Yu L, Zhou B. Chronic exposure to environmental levels of tribromophenol impairs zebrafish reproduction. Toxicol Appl Pharmacol. 2010;243:87-95 pubmed publisher
    ..The F(1)-generation larvae exhibited increased malformation, reduced survival, and retarded growth, suggesting that TBP in the aquatic environment has significant adverse effects on fish population. ..
  15. Xu T, Wang Q, Shi Q, Fang Q, Guo Y, Zhou B. Bioconcentration, metabolism and alterations of thyroid hormones of Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) in Zebrafish. Environ Toxicol Pharmacol. 2015;40:581-6 pubmed publisher
    ..The present study reveals that exposure to low concentrations of TDCPP can cause bioconcentration in fish, and TDCPP can be readily metabolized in liver. ..
  16. Wang Q, Chen Q, Zhou P, Li W, Wang J, Huang C, et al. Bioconcentration and metabolism of BDE-209 in the presence of titanium dioxide nanoparticles and impact on the thyroid endocrine system and neuronal development in zebrafish larvae. Nanotoxicology. 2014;8 Suppl 1:196-207 pubmed publisher
    ..g. myelin basic protein and ?1-tubulin). These results indicate nano-TiO2 enhances BDE-209 bioavailability and metabolism, leading to thyroid endocrine disruption and developmental neurotoxicity in zebrafish. ..
  17. Takezaki N, Figueroa F, Zaleska Rutczynska Z, Klein J. Molecular phylogeny of early vertebrates: monophyly of the agnathans as revealed by sequences of 35 genes. Mol Biol Evol. 2003;20:287-92 pubmed
    ..Our analyses also give a strong support for the separation of Chondrichthyes (cartilaginous fishes) before the divergence of Osteichthyes (bony fishes) from the other gnathostomes...
  18. Fitzgerald J, Jameson H, Fowler V, Bond G, Bickley L, Webster T, et al. Hypoxia Suppressed Copper Toxicity during Early Development in Zebrafish Embryos in a Process Mediated by the Activation of the HIF Signaling Pathway. Environ Sci Technol. 2016;50:4502-12 pubmed publisher
    ..These findings change our understanding of the current and future impacts of worldwide oxygen depletion on fish communities challenged by anthropogenic toxicants. ..
  19. Provost E, Weier C, Leach S. Multiple ribosomal proteins are expressed at high levels in developing zebrafish endoderm and are required for normal exocrine pancreas development. Zebrafish. 2013;10:161-9 pubmed publisher