ripk1l

Summary

Gene Symbol: ripk1l
Description: receptor (TNFRSF)-interacting serine-threonine kinase 1, like
Alias: rip1, si:ch211-241e1.1, receptor-interacting serine/threonine-protein kinase 1, Ripk1, receptor-interacting 1
Species: zebrafish

Top Publications

  1. Sullivan C, Postlethwait J, Lage C, Millard P, Kim C. Evidence for evolving Toll-IL-1 receptor-containing adaptor molecule function in vertebrates. J Immunol. 2007;178:4517-27 pubmed
    ..These studies provide evidence, for the first time, of the evolving function of a vertebrate TLR pathway. ..
  2. Roca F, Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell. 2013;153:521-34 pubmed publisher
    ..TNF excess induces mitochondrial reactive oxygen species (ROS) in infected macrophages through RIP1-RIP3-dependent pathways...
  3. Zhou Z, Sun L. Edwardsiella tarda-Induced Inhibition of Apoptosis: A Strategy for Intracellular Survival. Front Cell Infect Microbiol. 2016;6:76 pubmed publisher
    ..tarda prevents apoptosis in teleost as a strategy for intracellular survival, and that some putative apoptotic genes of teleost function in the apoptosis pathway probably in a manner similar to that in mammalian systems. ..
  4. Wang W, Hong J, Lin G, Liu W, Gong H, Lu M, et al. Stage-specific expression of TNF? regulates bad/bid-mediated apoptosis and RIP1/ROS-mediated secondary necrosis in Birnavirus-infected fish cells. PLoS ONE. 2011;6:e16740 pubmed publisher
    ..We found that IPNV infection can regulate Bad/Bid-mediated apoptotic and Rip1/ROS-mediated necrotic death pathways via the up-regulation of TNF? in zebrafish ZF4 cells...
  5. Viringipurampeer I, Shan X, Gregory Evans K, Zhang J, Mohammadi Z, Gregory Evans C. Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish. Cell Death Differ. 2014;21:665-75 pubmed publisher
    ..In pde6c(w59) mutant zebrafish, cone photoreceptors expressed high levels of receptor-interacting protein kinase 1 (RIP1) and receptor-interacting protein kinase 3 (RIP3) kinases, key regulators of necroptotic cell death...
  6. Srivastava N, Shelly A, Kumar M, Pant A, Das B, Majumdar T, et al. Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish. Cell Death Discov. 2017;3:17067 pubmed publisher
    ..Inside the cytosol, A. hydrophila avoids detection by suppressing NLRs, facilitating its survival and ensuing pathogenesis. ..