Gene Symbol: rel
Description: v-rel avian reticuloendotheliosis viral oncogene homolog
Alias: c-rel, zgc:100833, proto-oncogene c-Rel, v-rel reticuloendotheliosis viral oncogene homolog
Species: zebrafish

Top Publications

  1. Pan C, Wu J, Hui C, Lin C, Chen J. Insights into the antibacterial and immunomodulatory functions of the antimicrobial peptide, epinecidin-1, against Vibrio vulnificus infection in zebrafish. Fish Shellfish Immunol. 2011;31:1019-25 pubmed publisher
    ..This study demonstrates the use of epinecidin-1 to develop inactivated material for fish bacterial infections which can provide guidelines for the future design of epinecidin-1-bacterial formulations for various in vivo applications. ..
  2. Udayangani R, Dananjaya S, Fronte B, Kim C, Lee J, De Zoysa M. Feeding of nano scale oats ?-glucan enhances the host resistance against Edwardsiella tarda and protective immune modulation in zebrafish larvae. Fish Shellfish Immunol. 2017;60:72-77 pubmed publisher
    ..showed up-regulation of immune functional genes including TNF-?, IL-1?, ?-defensin, lysozyme, IL 10, IL 12 and C-Rel indicating higher survival rate could be due to stronger immunomodulatory function of NBG (500 ?g/mL)...
  3. Wang C, Chen Y, Bian W, Xie S, Qi G, Liu L, et al. Deletion of mstna and mstnb impairs the immune system and affects growth performance in zebrafish. Fish Shellfish Immunol. 2018;72:572-580 pubmed publisher
    ..tarda exposure except nfkb1, c-rel and tnf?...
  4. Correa R, Tergaonkar V, Ng J, Dubova I, Izpisua Belmonte J, Verma I. Characterization of NF-kappa B/I kappa B proteins in zebra fish and their involvement in notochord development. Mol Cell Biol. 2004;24:5257-68 pubmed
    ..Our study illustrates the conservation and compatibility of NF-kappa B/I kappa B proteins among vertebrates and the importance of NF-kappa B pathway in mesoderm formation during early embryogenesis. ..
  5. Li S, Guo X, Lu L, Lu X, Wu N, Zhang Y. Regulation pattern of fish irf4 (the gene encoding IFN regulatory factor 4) by STAT6, c-Rel and IRF4. Dev Comp Immunol. 2015;51:65-73 pubmed publisher
    ..In this study, we examined the regulatory patterns of zebrafish irf4a and irf4b by STAT6 and c-Rel. Firstly, expression of irf4a and irf4b was monitored in several tissues at mRNA level...
  6. Karra R, Knecht A, Kikuchi K, Poss K. Myocardial NF-κB activation is essential for zebrafish heart regeneration. Proc Natl Acad Sci U S A. 2015;112:13255-60 pubmed publisher
    ..Our results implicate NF-κB signaling as a key node between cardiac injury and tissue regeneration. ..
  7. Bagheri H, Badduke C, Qiao Y, Colnaghi R, Abramowicz I, Alcantara D, et al. Identifying candidate genes for 2p15p16.1 microdeletion syndrome using clinical, genomic, and functional analysis. JCI Insight. 2016;1:e85461 pubmed
    ..Recent reports pointed to 4 genes (XPO1, USP34, BCL11A, and REL) that were included, alone or in combination, in the smallest deletions causing the syndrome...
  8. Udayangani R, Dananjaya S, Nikapitiya C, Heo G, Lee J, De Zoysa M. Metagenomics analysis of gut microbiota and immune modulation in zebrafish (Danio rerio) fed chitosan silver nanocomposites. Fish Shellfish Immunol. 2017;66:173-184 pubmed publisher