Gene Symbol: rcvrn2
Description: recoverin 2
Alias: fk53a03, rcv1, rcv2a, wu:fk53a03, zgc:73121, recoverin 2, recoverin-2a
Species: zebrafish
Products:     rcvrn2

Top Publications

  1. Linder B, Dill H, Hirmer A, Brocher J, Lee G, Mathavan S, et al. Systemic splicing factor deficiency causes tissue-specific defects: a zebrafish model for retinitis pigmentosa. Hum Mol Genet. 2011;20:368-77 pubmed publisher
    ..Hence, various routes affecting the tri-snRNP can elicit tissue-specific gene expression defects and lead to the RP phenotype. ..
  2. Palczewski K, Sokal I, Baehr W. Guanylate cyclase-activating proteins: structure, function, and diversity. Biochem Biophys Res Commun. 2004;322:1123-30 pubmed
    ..In the absence of GCAP2, GCAP1 supports the generation of wild-type flash responses in both rod and cone cells. Recent progress revealed an unexpected complexity of the GC-GCAP system, pointing, out a number of unsolved questions. ..
  3. Yin J, Brocher J, Fischer U, Winkler C. Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa. Mol Neurodegener. 2011;6:56 pubmed publisher
    ..Analyzing the AD5 effects in our animal model in vivo, our data imply that aberrant splicing of distinct retinal transcripts contributes to the observed retina defects. ..
  4. Zhang Y, Bonilla S, Chong L, Leung Y. Irx7, a Smarca4-regulated gene for retinal differentiation, regulates other genes controlled by Smarca4 in zebrafish retinas. Gene Expr Patterns. 2013;13:177-82 pubmed publisher
    ..role of irx7 on 13 genes including aanat2, barhl2, bhlhe22, cdh11, ckmt1, gnat1, irx4a, ndrg1a, nme2l, pbx1a, rcv1, robo2 and tfap2a...
  5. Zang J, Keim J, Kastenhuber E, Gesemann M, Neuhauss S. Recoverin depletion accelerates cone photoresponse recovery. Open Biol. 2015;5: pubmed publisher
    ..Here we identify four recoverin genes in the zebrafish genome, rcv1a, rcv1b, rcv2a and rcv2b, and investigate their role in modulating the cone phototransduction cascade...
  6. Lu Z, Hu X, Liu F, Soares D, Liu X, Yu S, et al. Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy. Sci Rep. 2017;7:46098 pubmed publisher