Gene Symbol: pvalb7
Description: parvalbumin 7
Alias: pvalb, zgc:92782, parvalbumin-7, parvalbumin alpha, parvalbumin-4a
Species: zebrafish

Top Publications

  1. Bae Y, Kani S, Shimizu T, Tanabe K, Nojima H, Kimura Y, et al. Anatomy of zebrafish cerebellum and screen for mutations affecting its development. Dev Biol. 2009;330:406-26 pubmed publisher
    ..Our data provide a platform for future studies of zebrafish cerebellar development. ..
  2. Kani S, Bae Y, Shimizu T, Tanabe K, Satou C, Parsons M, et al. Proneural gene-linked neurogenesis in zebrafish cerebellum. Dev Biol. 2010;343:1-17 pubmed publisher
    ..Our data indicate that proneural gene-linked neurogenesis is evolutionarily conserved in the cerebellum among vertebrates, and that the continuously generated neurons help remodel neural circuits in the adult zebrafish cerebellum. ..
  3. Wan J, Yourshaw M, Mamsa H, Rudnik Schoneborn S, Menezes M, Hong J, et al. Mutations in the RNA exosome component gene EXOSC3 cause pontocerebellar hypoplasia and spinal motor neuron degeneration. Nat Genet. 2012;44:704-8 pubmed publisher
  4. Kress S, Biechl D, Wullimann M. Combinatorial analysis of calcium-binding proteins in larval and adult zebrafish primary olfactory system identifies differential olfactory bulb glomerular projection fields. Brain Struct Funct. 2015;220:1951-70 pubmed publisher
    ..One singular glomerulus (mdG2) exhibits S100 and parvalbumin-positive fibers, apparently originating from all crypt cells plus some microvillous OSNs. Arguments for various olfactory labeled lines are discussed. ..
  5. Huang M, Wang T, Liu Y, Li Y, Chi T, Chou C, et al. Roles of carbonic anhydrase 8 in neuronal cells and zebrafish. Biochim Biophys Acta. 2014;1840:2829-42 pubmed publisher
  6. Marín Juez R, Rovira M, Crespo D, van der Vaart M, Spaink H, Planas J. GLUT2-mediated glucose uptake and availability are required for embryonic brain development in zebrafish. J Cereb Blood Flow Metab. 2015;35:74-85 pubmed publisher
    ..These results indicate that glut2 has an essential role during brain development by facilitating the uptake and availability of glucose and support the involvement of glut2 in brain glucose sensing. ..
  7. Yanicostas C, Barbieri E, Hibi M, Brice A, Stevanin G, Soussi Yanicostas N. Requirement for zebrafish ataxin-7 in differentiation of photoreceptors and cerebellar neurons. PLoS ONE. 2012;7:e50705 pubmed publisher
    ..These findings further suggest that altered protein function may play a role in the pathophysiology of the disease, an important step toward the development of future therapeutic strategies. ..
  8. Li Z, You J, Luo Y, Wu J. Purification and characterization of parvalbumin isotypes from grass carp (Ctenopharyngodon idella). J Agric Food Chem. 2014;62:6212-8 pubmed publisher
    ..PVII is the dominant allergen, but it was liable to gastrointestinal enzymes as PVIII; however, PVI was resistant to pepsin digestion. A further study is to characterize the epitopes of PVII, the dominant allergen. ..
  9. Modrell M, Lyne M, Carr A, Zakon H, Buckley D, Campbell A, et al. Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome. elife. 2017;6: pubmed publisher
    ..Overall, our results illuminate ampullary organ development, physiology and evolution. ..

More Information


  1. Friedberg F. Parvalbumin isoforms in zebrafish. Mol Biol Rep. 2005;32:167-75 pubmed
    ..A bifurcation of isoforms into 1 and 4; 2 and 3; 6 and 7; 8 and 9 appears to have occurred simultaneously in more recent time, i.e. perhaps approximately 60 mys ago when primates and rodents branched. ..
  2. Zhang C, Ojiaku P, Cole G. Forebrain and hindbrain development in zebrafish is sensitive to ethanol exposure involving agrin, Fgf, and sonic hedgehog function. Birth Defects Res A Clin Mol Teratol. 2013;97:8-27 pubmed publisher
  3. Liao W, Cheng C, Hung K, Chiu W, Chen G, Hwang P, et al. Protein tyrosine phosphatase receptor type O (Ptpro) regulates cerebellar formation during zebrafish development through modulating Fgf signaling. Cell Mol Life Sci. 2013;70:2367-81 pubmed publisher
    ..Therefore, our findings demonstrate that Ptpro activity is required for patterning the zebrafish embryonic brain. Specifically, Ptpro regulates cerebellar formation during zebrafish development through modulating Fgf signaling. ..
  4. Kyöstilä K, Syrjä P, Jagannathan V, Chandrasekar G, Jokinen T, Seppälä E, et al. A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease. PLoS Genet. 2015;11:e1005169 pubmed publisher
    ..Furthermore, our results reveal a novel candidate gene for human neurodegeneration and enable the development of a genetic test for veterinary diagnostic and breeding purposes. ..