Gene Symbol: prl2
Description: prolactin 2
Alias: si:dkey-261e22.3, prolactin 2, PRL-L
Wang Y, Li J, Yan Kwok A, Ge W, Leung F. A novel prolactin-like protein (PRL-L) gene in chickens and zebrafish: cloning and characterization of its tissue expression. Gen Comp Endocrinol. 2010;166:200-10 pubmed publisher
..Taken together, these findings strongly suggest that a novel PRL-like protein exists in some non-mammalian vertebrates and may play an important role in target tissues, such as extra-pituitary tissues of chickens and zebrafish. ..
Wong R, Oxendine S, Godwin J. Behavioral and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment. BMC Genomics. 2013;14:348 pubmed publisher
..This study provides data that could help identify common molecular mechanisms of fluoxetine action across animal taxa. ..
Chen M, Huang X, Yuen D, Cheng C. A study on the functional interaction between the GH/PRL family of polypeptides with their receptors in zebrafish: Evidence against GHR1 being the receptor for somatolactin. Mol Cell Endocrinol. 2011;337:114-21 pubmed publisher
..Specifically, zebrafish contains five ligands (GH, SL?, SL?, PRL1 and PRL2) and four cognate receptors including two GH receptors (GHR1 and GHR2) and two PRL receptors (PRLR1 and PRLR2)...
Li C, Chen X, Zhang Y, Ye H, Liu T. Molecular and expression characterization of growth hormone/prolactin family genes in the Prenant's schizothoracin. Mol Biol Rep. 2011;38:4595-602 pubmed publisher
..SpGH was expressed in nearly all tissues detected with the highest expression level in the pituitary. ..
Huang X, Hui M, Liu Y, Yuen D, Zhang Y, Chan W, et al
. Discovery of a novel prolactin in non-mammalian vertebrates: evolutionary perspectives and its involvement in teleost retina development. PLoS ONE. 2009;4:e6163 pubmed publisher
..view of its close phylogenetic relationship with PRL and also its ability to activate PRL receptor, we name it as PRL2 and the previously identified PRL as PRL1...