phf8

Summary

Gene Symbol: phf8
Description: PHD finger protein 8
Alias: zPHF8, histone lysine demethylase PHF8
Species: zebrafish

Top Publications

  1. Tsukada Y, Ishitani T, Nakayama K. KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development. Genes Dev. 2010;24:432-7 pubmed publisher
    ..Our findings identify KDM7 as a dual demethylase for H3K9 and H3K27 that functions as an eraser of silencing marks on chromatin during brain development...
  2. Qi H, Sarkissian M, Hu G, Wang Z, Bhattacharjee A, Gordon D, et al. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 2010;466:503-7 pubmed publisher
    ..b>PHF8 (PHD (plant homeo domain) finger protein 8) is a JmjC domain-containing protein and its mutations have been found ..