Gene Symbol: pcxb
Description: pyruvate carboxylase b
Alias: PYCb, pyc, wu:fb82g08, wu:fj85g01, pyruvate carboxylase, mitochondrial
Species: zebrafish
Products:     pcxb

Top Publications

  1. Craig P, Trudeau V, Moon T. Profiling hepatic microRNAs in zebrafish: fluoxetine exposure mimics a fasting response that targets AMP-activated protein kinase (AMPK). PLoS ONE. 2014;9:e95351 pubmed publisher
    ..This has important implications for the heath of fish because concentrations of SSRIs in aquatic ecosystems are continually increasing. ..
  2. Gonzalez P, Dominique Y, Massabuau J, Boudou A, Bourdineaud J. Comparative effects of dietary methylmercury on gene expression in liver, skeletal muscle, and brain of the zebrafish (Danio rerio). Environ Sci Technol. 2005;39:3972-80 pubmed
    ..The expression of the metallothionein mt2 and the DNA repair rad51 genes was up-regulated in liver between 21 and 63 days, whereas in skeletal muscle, mt2 remained uninduced, and gadd and rad51 were found to be repressed. ..
  3. Pradhan A, Asnake S, Kharlyngdoh J, Modig C, Olsson P. In silico and biological analysis of anti-androgen activity of the brominated flame retardants ATE, BATE and DPTE in zebrafish. Chem Biol Interact. 2015;233:35-45 pubmed publisher
    ..Genes involved in steroidogenesis were also down-regulated by these BFRs. In view of this, the impact of these BFRs on humans and wildlife needs further analysis. ..
  4. Sandoval I, Delacruz R, Miller B, Hill S, Olson K, Gabriel A, et al. A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC). elife. 2017;6: pubmed publisher
    ..Our data demonstrate a novel role for apc in pyruvate metabolism and that pyruvate metabolism dictates intestinal cell fate and differentiation decisions downstream of apc. ..
  5. Yoder J, Litman G. The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13. Gene. 2000;261:235-42 pubmed
    ..These six genes, along with men1, fgf3 and cycd1 define two regions of conserved synteny between linkage group 7 and 11q13. ..
  6. Gonzalez P, Baudrimont M, Boudou A, Bourdineaud J. Comparative effects of direct cadmium contamination on gene expression in gills, liver, skeletal muscles and brain of the zebrafish (Danio rerio). Biometals. 2006;19:225-35 pubmed
    ..Three additional genes, c-jun, pyc and tap, were up-regulated in muscles at day 21 whereas bax, gadd and rad51 had returned to basal levels...
  7. Nguyen V, Fuse Y, Tamaoki J, Akiyama S, Muratani M, Tamaru Y, et al. Conservation of the Nrf2-Mediated Gene Regulation of Proteasome Subunits and Glucose Metabolism in Zebrafish. Oxid Med Cell Longev. 2016;2016:5720574 pubmed publisher
    ..These findings implied that the Nrf2-mediated regulation of the proteasome subunits and glucose metabolism is evolutionarily conserved among vertebrates. ..