Gene Symbol: pbx1a
Description: pre-B-cell leukemia homeobox 1a
Alias: fi29e01, pbx1b, wu:fi29e01, zgc:55265, pre-B-cell leukemia homeobox 1a, pre-B-cell leukemia transcription factor 1a, pre-B-cell leukemia transcription factor 1b
Waskiewicz A, Rikhof H, Moens C. Eliminating zebrafish pbx proteins reveals a hindbrain ground state. Dev Cell. 2002;3:723-33 pubmed
Palti Y, Rodriguez M, Gahr S, Hansen J. Evolutionary history of the ABCB2 genomic region in teleosts. Dev Comp Immunol. 2007;31:483-98 pubmed
..Our analysis indicates that this region was generated during the teleost-specific duplication event while also providing insight about potential MH paralogous regions in teleosts...
Teoh P, Shu Chien A, Chan W. Pbx1 is essential for growth of zebrafish swim bladder. Dev Dyn. 2010;239:865-74 pubmed publisher
..However, the expression of anxa5 was completely abolished by pbx1 knockdown at 60 hpf suggesting that pbx1 may be required during the late stage of swim bladder development...
Cvejic A, Serbanovic Canic J, Stemple D, Ouwehand W. The role of meis1 in primitive and definitive hematopoiesis during zebrafish development. Haematologica. 2011;96:190-8 pubmed publisher
..These results imply that meis1, jointly with pbx1, regulates primitive hematopoiesis as well as vascular development. ..
McGrail M, Hatler J, Kuang X, Liao H, Nannapaneni K, Watt K, et al
. Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish. PLoS ONE. 2011;6:e18826 pubmed publisher
..The zebrafish T2/OncZ cancer model will be useful for identifying novel and conserved genetic drivers of human cancers. ..
Zhang Y, Bonilla S, Chong L, Leung Y. Irx7, a Smarca4-regulated gene for retinal differentiation, regulates other genes controlled by Smarca4 in zebrafish retinas. Gene Expr Patterns. 2013;13:177-82 pubmed publisher
..regulatory role of irx7 on 13 genes including aanat2, barhl2, bhlhe22, cdh11, ckmt1, gnat1, irx4a, ndrg1a, nme2l, pbx1a, rcv1, robo2 and tfap2a...
Gerlai R, Poshusta T, Rampersad M, Fernandes Y, Greenwood T, Cousin M, et al
. Forward Genetic Screening Using Behavioral Tests in Zebrafish: A Proof of Concept Analysis of Mutants. Behav Genet. 2017;47:125-139 pubmed publisher
..We discuss the pros and cons of behavioral phenotyping and of the use of different forward genetic methods in biomedical research with zebrafish. ..
Xu J, Zhang R, Zhang T, Zhao G, Huang Y, Wang H, et al
. Copper impairs zebrafish swimbladder development by down-regulating Wnt signaling. Aquat Toxicol. 2017;192:155-164 pubmed publisher