pappab

Summary

Gene Symbol: pappab
Description: pregnancy-associated plasma protein A, pappalysin 1b
Alias: si:ch211-196f15.1, pregnancy-associated plasma protein A, pappalysin 1b
Species: zebrafish

Top Publications

  1. Kjaer Sorensen K, Engholm D, Kamei H, Morch M, Kristensen A, Zhou J, et al. Pregnancy-associated plasma protein A (PAPP-A) modulates the early developmental rate in zebrafish independently of its proteolytic activity. J Biol Chem. 2013;288:9982-92 pubmed publisher
    ..We conclude that Papp-a possesses biological functions independent of its proteolytic activity. Our data represent the first evidence for a non-proteolytic function of PAPP-A. ..
  2. Sugden W, Meissner R, Aegerter Wilmsen T, Tsaryk R, Leonard E, Bussmann J, et al. Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues. Nat Cell Biol. 2017;19:653-665 pubmed publisher
    ..Together, our data suggest that cell shape changes in response to biophysical cues act as an underlying principle allowing for the ordered patterning of tubular organs. ..