Genomes and Genes
Gene Symbol: opn1mw4
Description: opsin 1 (cone pigments), medium-wave-sensitive, 4
Alias: RH2-4, grops2, rh2.4, wu:fk64b02, zfgr2, green-sensitive opsin-4, green cone photoreceptor pigment 4, green-sensitive opsin 2, opsin RH2-4, opsin-1, medium-wave-sensitive 4, rhodopsin-like-2.4 cone opsin
- Tsujimura T, Chinen A, Kawamura S. Identification of a locus control region for quadruplicated green-sensitive opsin genes in zebrafish. Proc Natl Acad Sci U S A. 2007;104:12813-8 pubmed..5-kb region in the PAC clone conferred the highest expression for its proximal gene. The 0.5-kb region was thus designated as RH2-LCR analogous to the locus control region of the L-M opsin genes of primates. ..
- Fraser B, Duval M, Wang H, Allison W. Regeneration of cone photoreceptors when cell ablation is primarily restricted to a particular cone subtype. PLoS ONE. 2013;8:e55410 pubmed publisher..Our novel animal model provides control of ablation that will assist in identifying mechanisms required to replace cone photoreceptors clinically to restore daytime vision. ..
- Meng F, Braasch I, Phillips J, Lin X, Titus T, Zhang C, et al. Evolution of the eye transcriptome under constant darkness in Sinocyclocheilus cavefish. Mol Biol Evol. 2013;30:1527-43 pubmed publisher..These results show that the independent evolution of retinal degeneration in cavefish can occur by different developmental genetic mechanisms. ..
- Koyanagi M, Wada S, Kawano Yamashita E, Hara Y, Kuraku S, Kosaka S, et al. Diversification of non-visual photopigment parapinopsin in spectral sensitivity for diverse pineal functions. BMC Biol. 2015;13:73 pubmed publisher..Current findings could also provide an opportunity to understand the "color" preference of non-visual photoreception. ..
- Morrow J, Lazic S, Chang B. A novel rhodopsin-like gene expressed in zebrafish retina. Vis Neurosci. 2011;28:325-35 pubmed publisher..The discovery of a new previously uncharacterized opsin gene in zebrafish retina is surprising given its status as a model system for studies of vertebrate vision and visual development. ..
- Chinen A, Hamaoka T, Yamada Y, Kawamura S. Gene duplication and spectral diversification of cone visual pigments of zebrafish. Genetics. 2003;163:663-75 pubmed
- Kennedy M, Dunn F, Hurley J. Visual pigment phosphorylation but not transducin translocation can contribute to light adaptation in zebrafish cones. Neuron. 2004;41:915-28 pubmed..Immunocytochemical analyses revealed that neither light nor cytoplasmic Ca2+ influences the localization of transducin in zebrafish cones. ..