Gene Symbol: nucb2a
Description: nucleobindin 2a
Alias: cb638, nucb2, wu:fa03d10, nucleobindin-2
Hatef A, Shajan S, Unniappan S. Nutrient status modulates the expression of nesfatin-1 encoding nucleobindin 2A and 2B mRNAs in zebrafish gut, liver and brain. Gen Comp Endocrinol. 2015;215:51-60 pubmed publisher
Nesfatin-1 is a naturally occurring, 82-amino acid peptide processed from the precursor nucleobindin 2 (NUCB2), a highly conserved protein among vertebrates...
Falcinelli S, Rodiles A, Unniappan S, Picchietti S, Gioacchini G, Merrifield D, et al
. Probiotic treatment reduces appetite and glucose level in the zebrafish model. Sci Rep. 2016;6:18061 pubmed publisher
..rhamnosus in the treatment of impaired glucose tolerance and food intake disorders by gut microbiota manipulation. ..
Falcinelli S, Rodiles A, Hatef A, Picchietti S, Cossignani L, Merrifield D, et al
. Dietary lipid content reorganizes gut microbiota and probiotic L. rhamnosus attenuates obesity and enhances catabolic hormonal milieu in zebrafish. Sci Rep. 2017;7:5512 pubmed publisher
Macqueen D, Johnston I. An update on MyoD evolution in teleosts and a proposed consensus nomenclature to accommodate the tetraploidization of different vertebrate genomes. PLoS ONE. 2008;3:e1567 pubmed publisher
..We propose a sensible consensus nomenclature for vertebrate myod genes that accommodates polyploidization events in teleost and tetrapod lineages and is justified from a phylogenetic perspective...
Lin F, Zhou C, Chen H, Wu H, Xin Z, Liu J, et al
. Molecular characterization, tissue distribution and feeding related changes of NUCB2A/nesfatin-1 in Ya-fish (Schizothorax prenanti). Gene. 2014;536:238-46 pubmed publisher
..In the present study, we characterized the structure, distribution, and meal responsive of NUCB2A/nesfatin-1 in Ya-fish (Schizothorax prenanti) for the first time...
Nair N, Gerger C, Hatef A, Weber L, Unniappan S. Ultrasonography reveals in vivo dose-dependent inhibition of end systolic and diastolic volumes, heart rate and cardiac output by nesfatin-1 in zebrafish. Gen Comp Endocrinol. 2016;234:142-50 pubmed publisher
..Real-time quantitative PCR analysis found that the cardiac expression of NUCB2A mRNA in unfed fish decreased at 1h post-regular feeding time...