Gene Symbol: nod1
Description: nucleotide-binding oligomerization domain containing 1
Alias: nucleotide-binding oligomerization domain-containing protein 1, NLR-A1
- Howe K, Schiffer P, Zielinski J, Wiehe T, Laird G, Marioni J, et al. Structure and evolutionary history of a large family of NLR proteins in the zebrafish. Open Biol. 2016;6:160009 pubmed publisher..The NLR-B30.2 proteins represent a new family with diversity in the specific recognition module that is present in fishes in spite of the parallel existence of an adaptive immune system. ..
- Tandberg J, Lagos L, Langlete P, Berger E, Rishovd A, Roos N, et al. Comparative Analysis of Membrane Vesicles from Three Piscirickettsia salmonis Isolates Reveals Differences in Vesicle Characteristics. PLoS ONE. 2016;11:e0165099 pubmed publisher..salmonis derived MVs, highlighting strain-specific vesicle characteristics. The results further illustrate that the MV proteome from one bacterial strain is not representative of all bacterial strains within one species. ..
- Wang C, Chen Y, Bian W, Xie S, Qi G, Liu L, et al. Deletion of mstna and mstnb impairs the immune system and affects growth performance in zebrafish. Fish Shellfish Immunol. 2018;72:572-580 pubmed publisher..While each paralogue contributes to the response to bacterial insult, mstnb affects the immune system through activation of the NF-?B pathway, and mstna is likely to act upstream of NF-?B at some as yet unidentified target. ..
- Hu Y, Yu Z, Xue N, Nie P, Chang M. Expression and protective role of two novel NACHT-containing proteins in pathogen infection. Dev Comp Immunol. 2014;46:323-32 pubmed publisher..the expression of downstream signaling genes was not affected by the overexpression of NALPL1 or NALPL2, but NOD1 and MDA5 were upregulated by NALPL1 or NALPL2 overexpression, suggesting that they likely act in pathogen infection ..