Gene Symbol: nfil3
Description: nuclear factor, interleukin 3 regulated
Alias: E4BP4-1, zgc:100867, nuclear factor interleukin-3-regulated protein, E4 binding protein 4-1, E4BP4, ze4bp4-1
Species: zebrafish
Products:     nfil3

Top Publications

  1. Weng Y, Hsieh D, Kuo W, Lai T, Hsu H, Tsai C, et al. E4BP4 is a cardiac survival factor and essential for embryonic heart development. Mol Cell Biochem. 2010;340:187-94 pubmed publisher
    The bZIP transcription factor E4BP4, has been demonstrated to be a survival factor in pro-B lymphocytes. GATA factors play important roles in transducing the IL-3 survival signal and transactivating the downstream survival gene, E4BP4...
  2. Ben Moshe Z, Vatine G, Alon S, Tovin A, Mracek P, Foulkes N, et al. Multiple PAR and E4BP4 bZIP transcription factors in zebrafish: diverse spatial and temporal expression patterns. Chronobiol Int. 2010;27:1509-31 pubmed publisher
    ..The PAR subfamily of transcriptional activators and the related E4BP4 repressor belonging to the basic leucine zipper (bZIP) family are clock-controlled genes that are suggested to ..
  3. Li I, Chan C, Lu Y, Wu Y, Chen Y, Li G, et al. Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages. PLoS ONE. 2011;6:e20974 pubmed publisher
    ..Moreover, the regulation of differentiation of goblet cells in zebrafish intestine by Notch signaling at least partially mediated through Klf4a. ..
  4. Progatzky F, Taylor H, Bugeon L, Cassidy S, Radbruch A, Dallman M, et al. The role of Nfil3 in zebrafish hematopoiesis. Dev Comp Immunol. 2012;38:187-92 pubmed publisher
    b>Nfil3, a transcription factor that has an array of functions in immune cells, has been described as key regulator of CD8?(+) dendritic cell and natural killer cell development in mice...
  5. Shakes L, Du H, Wolf H, HATCHER C, Norford D, Precht P, et al. Using BAC transgenesis in zebrafish to identify regulatory sequences of the amyloid precursor protein gene in humans. BMC Genomics. 2012;13:451 pubmed publisher transgenes in zebrafish identified putative binding sites of two known transcription factor proteins, E4BP4/ NFIL3 and Forkhead, to be required for expression of appb...
  6. Yu H, Shen Y, Sun J, Xu X, Wang R, Xuan Y, et al. Molecular cloning and functional characterization of the NFIL3/E4BP4 transcription factor of grass carp, Ctenopharyngodon idella. Dev Comp Immunol. 2014;47:215-22 pubmed publisher
    b>NFIL3 (nuclear factor interleukin 3-regulated) is an important bZIP transcription factor in the immune response and immune cells' development. Here, we identified the NFIL3 gene from grass carp (Ctenopharyngodon idella; gcNFIL3)...