Gene Symbol: ndrg1a
Description: N-myc downstream regulated 1a
Alias: cb775, ndrg1, ndrg1a-1, ndrg1a-2, wu:fb60h02, zgc:63944, protein NDRG1, N-myc downstream regulated gene 1, N-myc downstream regulated gene 1a, n-myc downstream-regulated gene 1a-1, n-myc downstream-regulated gene 1a-2
Species: zebrafish
Products:     ndrg1a

Top Publications

  1. Hsiao C, You M, Guh Y, Ma M, Jiang Y, Hwang P. A positive regulatory loop between foxi3a and foxi3b is essential for specification and differentiation of zebrafish epidermal ionocytes. PLoS ONE. 2007;2:e302 pubmed
  2. Zhang Y, Bonilla S, Chong L, Leung Y. Irx7, a Smarca4-regulated gene for retinal differentiation, regulates other genes controlled by Smarca4 in zebrafish retinas. Gene Expr Patterns. 2013;13:177-82 pubmed publisher
    ..of the regulatory role of irx7 on 13 genes including aanat2, barhl2, bhlhe22, cdh11, ckmt1, gnat1, irx4a, ndrg1a, nme2l, pbx1a, rcv1, robo2 and tfap2a...
  3. Tan S, Cardoso Moreira M, Shi W, Zhang D, Huang J, Mao Y, et al. LTR-mediated retroposition as a mechanism of RNA-based duplication in metazoans. Genome Res. 2016;26:1663-1675 pubmed
  4. Crippa S, Nemir M, Ounzain S, Ibberson M, Berthonneche C, Sarre A, et al. Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways. Cardiovasc Res. 2016;110:73-84 pubmed publisher
    ..This novel strategy identifies a series of miRNAs and associated pathways, in particular miR-26a, which represent attractive therapeutic targets for inducing repair in the injured heart. ..
  5. Takita S, Wada Y, Kawamura S. Effects of NDRG1 family proteins on photoreceptor outer segment morphology in zebrafish. Sci Rep. 2016;6:36590 pubmed publisher
    ..Here, we show that NDRG1b and its paralog, NDRG1a-1, contribute to photoreceptor outer segment (OS) formation in zebrafish...
  6. Weiner A, Scampoli N, Calcaterra N. Fishing the molecular bases of Treacher Collins syndrome. PLoS ONE. 2012;7:e29574 pubmed publisher
    ..This experimental condition may facilitate the study of the disease etiology during embryonic development. ..
  7. Li R, Traver D, Matthes T, Bertrand J. Ndrg1b and fam49ab modulate the PTEN pathway to control T-cell lymphopoiesis in the zebrafish. Blood. 2016;128:3052-3060 pubmed publisher
  8. Kuechlin S, Schoels M, Slanchev K, Lassmann S, Walz G, Yakulov T. EpCAM controls morphogenetic programs during zebrafish pronephros development. Biochem Biophys Res Commun. 2017;487:209-215 pubmed publisher
    ..Gene ontology analysis revealed that EpCAM controls various developmental programs, including uretric bud development, morphogenesis of branching epithelium, regulation of cell differentiation and cilium morphogenesis. ..
  9. Shen L, Chen F, Zhang Y, Cao L, Kuang Y, Zhong M, et al. MYCN transgenic zebrafish model with the characterization of acute myeloid leukemia and altered hematopoiesis. PLoS ONE. 2013;8:e59070 pubmed publisher
    ..N-Myc downstream regulated gene 1 (NDRG1), negatively controlled by MYCN in human and functionally involved in neutrophil maturation, was significantly ..

More Information


  1. Chen C, Lin D, Cheng C, Lin C, Lo Y, Yen C, et al. Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish. Oncotarget. 2014;5:6300-11 pubmed
    ..Our findings and other characteristics of zebrafish, including optical clarity and small molecule treatment, provide the future utility of this model for easy and non-invasive detection and for identification of new anti-cancer drug. ..