Gene Symbol: mir143-1
Description: microRNA 143-1
Deacon D, Nevis K, Cashman T, Zhou Y, Zhao L, Washko D, et al
. The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesis. Development. 2010;137:1887-96 pubmed publisher
..Together, our data uncover the miR-143-add3 genetic pathway as essential for cardiac chamber formation and function through active adjustment of myocardial cell morphology. ..
Miyasaka K, Kida Y, Banjo T, Ueki Y, Nagayama K, Matsumoto T, et al
. Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143. Mech Dev. 2011;128:18-28 pubmed publisher
..Our data uncover a novel epigenetic link between heartbeat and cardiac development, with miR-143 as an essential component of the mechanotransduction cascade. ..
Li J, Liu J, Zhang Y, Wang X, Li W, Zhang H, et al
. Screening on the differentially expressed miRNAs in zebrafish (Danio rerio) exposed to trace ?-diketone antibiotics and their related functions. Aquat Toxicol. 2016;178:27-38 pubmed publisher
..In general, chronic DKA-exposure resulted in comprehensively toxic effects on larval and adult zebrafish tissues, especially for nervous system. ..
Müller Deile J, Gellrich F, Schenk H, Schroder P, Nyström J, Lorenzen J, et al
. Overexpression of TGF-? Inducible microRNA-143 in Zebrafish Leads to Impairment of the Glomerular Filtration Barrier by Targeting Proteoglycans. Cell Physiol Biochem. 2016;40:819-830 pubmed
..Podocyte-derived miR-143 is a mediator for paracrine and autocrine cross talk between podocytes and glomerular endothelial cells and can alter expression of glomerular glycocalyx proteins. ..