meis3

Summary

Gene Symbol: meis3
Description: myeloid ecotropic viral integration site 3
Alias: NH10, fc22g05, id:ibd3530, meis3.1, wu:fc22g05, homeobox protein Meis3
Species: zebrafish

Top Publications

  1. ncbi Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm
    Tetsuhiro Kudoh
    Department of Anatomy and Developmental Biology, University College London, Gower St, London WC1E 6BT, UK
    Development 129:4335-46. 2002
  2. pmc TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm
    Phillip diIorio
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Dev Biol 304:221-31. 2007
  3. doi Hmx4 regulates Sonic hedgehog signaling through control of retinoic acid synthesis during forebrain patterning
    Patricia A Gongal
    Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada
    Dev Biol 355:55-64. 2011
  4. ncbi Zebrafish model of holoprosencephaly demonstrates a key role for TGIF in regulating retinoic acid metabolism
    Patricia A Gongal
    Department of Biological Sciences, University of Alberta, Edmonton, Canada
    Hum Mol Genet 17:525-38. 2008
  5. pmc Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development
    Rosa A Uribe
    Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125
    Mol Biol Cell 26:3728-40. 2015
  6. pmc TALE factors poise promoters for activation by Hox proteins
    Seong Kyu Choe
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Dev Cell 28:203-11. 2014
  7. pmc The role of Zic transcription factors in regulating hindbrain retinoic acid signaling
    Danna L Drummond
    Department of Biological Sciences, University of Alberta, CW405, Edmonton, AB T6G 2E9, Canada
    BMC Dev Biol 13:31. 2013
  8. ncbi Variable Meis-dependence among paralog group-1 Hox proteins
    Seong Kyu Choe
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA
    Biochem Biophys Res Commun 331:1384-91. 2005
  9. pmc Cell type and tissue specific function of islet genes in zebrafish pancreas development
    Armin Wilfinger
    Institute for Molecular Biology CMBI, University of Innsbruck, Technikerstr 25, 6020 Innsbruck, Austria
    Dev Biol 378:25-37. 2013
  10. ncbi Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development
    Isabelle Manfroid
    GIGA Research Unité de Biologie Moleculaire et Génie Génétique, Tour B34, Universite de Liege, B 4000 Sart Tilman, Belgium
    Development 134:4011-21. 2007

Scientific Experts

  • Armin Wilfinger
  • Tetsuhiro Kudoh
  • Lisa Maves
  • Curtis R French
  • Isabelle Manfroid
  • Seong Kyu Choe
  • CHARLES G SAGERSTROM
  • Patricia A Gongal
  • Andrew J Waskiewicz
  • Rosa A Uribe
  • Danna L Drummond
  • Carlos Cruz
  • Aline Stedman
  • Emily S Noël
  • Phillip diIorio
  • Nicole M Roy
  • Marianne E Bronner
  • Franck Ladam
  • Caroline S Cheng
  • Jennifer C Hocking
  • Lisa B Prichard
  • Lyndsay G Selland
  • N Vlachakis
  • Karyn M Berry-Wynne
  • Laura M Pillay
  • Lindsey D March
  • Hiroyuki Kagechika
  • Vanessa L Holly
  • Igor B Dawid
  • Stephen W Wilson
  • Eric S Weinberg
  • Shingo Maegawa
  • Isabelle Anselme
  • Emmanuelle Havis
  • Sylvie Schneider-Maunoury
  • Peiyuan Lu
  • Michel Wassef
  • Mako Nakamura
  • Jinhyup Lee
  • Virginie Lecaudey
  • Pascale Gilardi-Hebenstreit
  • Heather Verkade
  • P Duc Si Dong
  • Derek L Stemple
  • Elisabeth Busch-Nentwich
  • Antonio Casal-Sueiro
  • Elke A Ober
  • Kristen Alexa
  • Letitiah Etheridge
  • C G Sagerstrom
  • S K Choe

Detail Information

Publications18

  1. ncbi Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm
    Tetsuhiro Kudoh
    Department of Anatomy and Developmental Biology, University College London, Gower St, London WC1E 6BT, UK
    Development 129:4335-46. 2002
    ..Using these two genes, as well as otx2 and meis3 as anterior and posterior markers, we show that Fgf and Wnt signals suppress expression of anterior genes, ..
  2. pmc TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm
    Phillip diIorio
    Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Dev Biol 304:221-31. 2007
    ..We find that expression of meis3, a TALE class homeodomain gene, coincides with shh expression in the endoderm of zebrafish embryos...
  3. doi Hmx4 regulates Sonic hedgehog signaling through control of retinoic acid synthesis during forebrain patterning
    Patricia A Gongal
    Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada
    Dev Biol 355:55-64. 2011
    ..We propose that Hmx4 is a critical regulator of retinoic acid synthesis in a developing embryo, and that this regulation is essential for controlling Shh signaling and forebrain development...
  4. ncbi Zebrafish model of holoprosencephaly demonstrates a key role for TGIF in regulating retinoic acid metabolism
    Patricia A Gongal
    Department of Biological Sciences, University of Alberta, Edmonton, Canada
    Hum Mol Genet 17:525-38. 2008
    ..The consequences of abnormal RA levels for forebrain patterning are profound, and imply that in human patients with TGIF deficiencies, increased forebrain RA levels contribute to the development of HPE...
  5. pmc Meis3 is required for neural crest invasion of the gut during zebrafish enteric nervous system development
    Rosa A Uribe
    Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125
    Mol Biol Cell 26:3728-40. 2015
    ..Here we show that the transcription factor meis3 is expressed along vagal neural crest pathways...
  6. pmc TALE factors poise promoters for activation by Hox proteins
    Seong Kyu Choe
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA
    Dev Cell 28:203-11. 2014
    ..We conclude that TALE factors access promoters during early embryogenesis to poise them for activation but that Hox proteins are required to trigger efficient transcription. ..
  7. pmc The role of Zic transcription factors in regulating hindbrain retinoic acid signaling
    Danna L Drummond
    Department of Biological Sciences, University of Alberta, CW405, Edmonton, AB T6G 2E9, Canada
    BMC Dev Biol 13:31. 2013
    ....
  8. ncbi Variable Meis-dependence among paralog group-1 Hox proteins
    Seong Kyu Choe
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA
    Biochem Biophys Res Commun 331:1384-91. 2005
    ..Upon addition of Meis3, Hoxb1b mimics the more severe Hoxb1a phenotype, indicating that Hoxb1b requires higher Meis levels than Hoxb1a...
  9. pmc Cell type and tissue specific function of islet genes in zebrafish pancreas development
    Armin Wilfinger
    Institute for Molecular Biology CMBI, University of Innsbruck, Technikerstr 25, 6020 Innsbruck, Austria
    Dev Biol 378:25-37. 2013
    ..The normal expression of the pancreas mesenchyme markers meis3, fgf10 and fgf24 in isl1/2 depleted embryos suggests that this activity is independent of isl-gene function in ..
  10. ncbi Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development
    Isabelle Manfroid
    GIGA Research Unité de Biologie Moleculaire et Génie Génétique, Tour B34, Universite de Liege, B 4000 Sart Tilman, Belgium
    Development 134:4011-21. 2007
    ....
  11. pmc Organ-specific requirements for Hdac1 in liver and pancreas formation
    Emily S Noël
    National Institute for Medical Research, Division of Developmental Biology, The Ridgeway, Mill Hill, London, UK
    Dev Biol 322:237-50. 2008
    ..These findings establish zebrafish as a tractable system to investigate chromatin remodelling factor functions in controlling gene expression programmes in vertebrate endodermal organogenesis...
  12. pmc Pbx acts with Hand2 in early myocardial differentiation
    Lisa Maves
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Dev Biol 333:409-18. 2009
    ..Our findings demonstrate new roles for Pbx proteins in vertebrate cardiac development and also provide new insight into connections between the transcriptional regulation of skeletal and cardiac muscle differentiation programs...
  13. pmc Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis
    Seong Kyu Choe
    Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, LRB822, Worcester, MA 01605, USA
    Dev Cell 17:561-7. 2009
    ..We conclude that Meis acts, at least in part, by controlling access of HDAC and CBP to Hox-regulated promoters...
  14. pmc Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish embryos
    Carlos Cruz
    School of Biosciences, University of Exeter, Devon EX4 4SP, UK
    Proc Natl Acad Sci U S A 107:3564-9. 2010
    ..We conclude that eve1 is crucial for the organization of the antero-posterior and dorso-ventral axis in the gastrula ectoderm and also has trunk- and tail-promoting activity...
  15. pmc Pbx homeodomain proteins pattern both the zebrafish retina and tectum
    Curtis R French
    Department of Biological Sciences, University of Alberta, Edmonton, Canada
    BMC Dev Biol 7:85. 2007
    ..Although previous results have demonstrated that Pbx is required for proper eye size, functions in regulating retinal cell identity and patterning have not yet been examined...
  16. ncbi An early Fgf signal required for gene expression in the zebrafish hindbrain primordium
    Nicole M Roy
    Department of Biochemistry and Molecular Pharmacology, and Program in Neuroscience, University of Massachusetts Medical School, 364 Plantation Street LRB 822, Worcester, MA 01605, USA
    Brain Res Dev Brain Res 148:27-42. 2004
    ..Our results demonstrate an early role for Fgf signaling and reveal a dynamic relationship between the RA and Fgf signaling pathways during hindbrain development...
  17. ncbi Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish
    N Vlachakis
    Department of Biochemistry and Molecular Pharmacology, and Program in Neuroscience, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Development 128:1299-312. 2001
    ..Here we demonstrate that Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish...
  18. doi A functional interaction between Irx and Meis patterns the anterior hindbrain and activates krox20 expression in rhombomere 3
    Aline Stedman
    CNRS UMR7622, Laboratoire de Biologie du Developpement, Universite Pierre et Marie Curie, Bâtiment C 7ème étage, Boite 24, 9 quai Saint Bernard, 75005 Paris, France
    Dev Biol 327:566-77. 2009
    ..Together, our data point to an essential function of Iroquois transcription factors in krox20 activation and, more generally, in anterior hindbrain specification...