Gene Symbol: meis2
Description: Meis homeobox 2b
Alias: meis2, meis2.1, Meis homeobox 2b, meis homeobox 2b, myeloid ecotropic viral integration site 2.1, myeloid ecotropic viral integration site 2b
Zerucha T, Prince V. Cloning and developmental expression of a zebrafish meis2 homeobox gene. Mech Dev. 2001;102:247-50 pubmed
We show here that a zebrafish meis2 gene homolog has a dynamic expression pattern in the developing mesoderm and central nervous system. Meis family homeodomain proteins are known to act as cofactors with other homeodomain proteins...
Bessa J, Tavares M, Santos J, Kikuta H, Laplante M, Becker T, et al
. meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye. Development. 2008;135:799-803 pubmed publisher
Moens C, Prince V. Constructing the hindbrain: insights from the zebrafish. Dev Dyn. 2002;224:1-17 pubmed
..As we will discuss, work in the zebrafish has elucidated inductive events that specify the presumptive hindbrain domain and has identified genes required for hindbrain segmentation and the specification of segment identities. ..
Santos J, Fonseca N, Vieira C, Vieira J, Casares F. Phylogeny of the teashirt-related zinc finger (tshz) gene family and analysis of the developmental expression of tshz2 and tshz3b in the zebrafish. Dev Dyn. 2010;239:1010-8 pubmed publisher
..and describe the developmental expressions of two of them, tshz2 and tshz3b, and compare them with meis1, meis2.1, meis2.2, pax6a, and pax6b expression patterns...
Rohrschneider M, Elsen G, Prince V. Zebrafish Hoxb1a regulates multiple downstream genes including prickle1b. Dev Biol. 2007;309:358-72 pubmed
..Using morpholino knock-down and cell transplantation, we demonstrate that the Hoxb1a target Prickle1b functions cell-autonomously to control facial neuron migration, a single aspect of r4 identity. ..
Paige S, Thomas S, Stoick Cooper C, Wang H, Maves L, Sandstrom R, et al
. A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell. 2012;151:221-32 pubmed publisher
..used this temporal chromatin signature to identify regulators of cardiac development, including the homeobox gene MEIS2. Using the zebrafish model, we demonstrate that MEIS2 is critical for proper heart tube formation and subsequent ..
Albuixech Crespo B, López Blanch L, Burguera D, Maeso I, Sánchez Arrones L, Moreno Bravo J, et al
. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. PLoS Biol. 2017;15:e2001573 pubmed publisher
..This suggests that these domains have a common developmental and evolutionary origin, as supported by functional experiments manipulating secondary organizers in zebrafish and mice. ..
Yoda H, Momoi A, Esguerra C, Meyer D, Driever W, Kondoh H, et al
. An expression pattern screen for genes involved in the induction of the posterior nervous system of zebrafish. Differentiation. 2003;71:152-62 pubmed
..Thus, our approach employing cDNA subtraction and subsequent expression pattern screening allows us to clone candidate genes involved in a novel signaling pathway contributing to the formation of the posterior nervous system. ..