Gene Symbol: mboat4
Description: membrane bound O-acyltransferase domain containing 4
Alias: ghrelin O-acyltransferase, GOAT
Species: zebrafish

Top Publications

  1. Hatef A, Yufa R, Unniappan S. Ghrelin O-Acyl Transferase in Zebrafish Is an Evolutionarily Conserved Peptide Upregulated During Calorie Restriction. Zebrafish. 2015;12:327-38 pubmed publisher
    ..is a multifunctional orexigenic hormone with a unique acyl modification enabled by ghrelin O-acyl transferase (GOAT). Ghrelin is well-characterized in nonmammals, and GOAT sequences of several fishes are available in the GenBank...
  2. Guillot R, Cortés R, Navarro S, Mischitelli M, García Herranz V, Sánchez E, et al. Behind melanocortin antagonist overexpression in the zebrafish brain: A behavioral and transcriptomic approach. Horm Behav. 2016;82:87-100 pubmed publisher
    ..The information provided herein will help to elucidate new central systems involved in control of obesity and should be of invaluable use for sustaining fish production systems. ..
  3. Gutierrez J, Solenberg P, Perkins D, Willency J, Knierman M, Jin Z, et al. Ghrelin octanoylation mediated by an orphan lipid transferase. Proc Natl Acad Sci U S A. 2008;105:6320-5 pubmed publisher
    ..Here we report the identification and characterization of human GOAT, the ghrelin O-acyl transferase...
  4. Falcinelli S, Rodiles A, Unniappan S, Picchietti S, Gioacchini G, Merrifield D, et al. Probiotic treatment reduces appetite and glucose level in the zebrafish model. Sci Rep. 2016;6:18061 pubmed publisher
    ..rhamnosus in the treatment of impaired glucose tolerance and food intake disorders by gut microbiota manipulation. ..